Results 11 to 20 of about 64,665 (70)

Risk factors and prognostic impact of new decompensated events in hospitalized patients with decompensated cirrhosis

BMC Gastroenterology
Background Decompensated cirrhosis (DC) is prone to recurrent episodes of decompensation following the initial event. This study aimed to identify the risk factors for subsequent decompensation and assess their impact on the outcomes of patients ...
Yan Lan, Yue Yu, Xiuding Zhang, Xianbin Xu, Xia Yu, Huilan Tu, Shaoheng Ye, Haoda Weng, Yu Shi, Jifang Sheng   +9 more
doaj   +1 more source

Clinical utility of the solid meal test during high-resolution esophageal manometry. A study in a Latin American population

Revista de Gastroenterología de México (English Edition)
Introduction and aims: The solid test meal (STM) is a challenge test that is done during esophageal manometry and appears to increase the diagnostic yield of the study.
K.R. García-Zermeño, J. Argüero, M. Amieva-Balmori, O. Rodríguez-Aguilera, A. Martínez-Conejo, M. Marcolongo, J.M. Remes-Troche   +6 more
doaj   +1 more source

The efficacy of CT-P13, a biosimilar of infliximab, in inflammatory bowel diseases: a systematic review and meta-analysis

BMC Gastroenterology
Background Since 2015, an infliximab biosimilar, CT-P13, has been approved for commercial use in many countries, easing the economic burden borne by society and patients.
Xinyue Hu, Xiaowei Tang, Limin Li, Lian Luo, Xinsen He, Qin Yan, Xiaolin Zhong   +6 more
doaj   +1 more source

Human milk oligosaccharides combine with Bifidobacterium longum to form the “golden shield” of the infant intestine: metabolic strategies, health effects, and mechanisms of action

Gut Microbes
Human milk oligosaccharides (HMOs) are the third most important nutrient in human milk and are the gold standard for infant nutrition. Due to the lack of an enzyme system capable of utilizing HMOs in the infant intestine, HMOs cannot be directly utilized.
Shuo Yang, Junwu Cai, Qian Su, Qiaohui Li, Xiangchen Meng   +4 more
doaj   +1 more source

B. vulgatus ameliorates high-fat diet-induced obesity through modulating intestinal serotonin synthesis and lipid absorption in mice

Gut Microbes
The consumption of high-fat diets (HFD) and an imbalance in gut microbiome are linked to obesity. However, the intricate connection between them and the underlying mechanisms involved in lipid digestion and absorption remain largely unclear.
Xinxin Wen, Xiaoyan Feng, Fang Xin, Rui An, Huanwei Huang, Liyuan Mao, Ping Liu, Jin Zhang, Haixia Huang, Xicheng Liu, Wei Wang   +10 more
doaj   +1 more source

Microbiota-derived small molecule genotoxins: host interactions and ecological impact in the gut ecosystem

Gut Microbes
The human intestinal tract is densely colonized by a microbial community that is subject to intense competition. Bacteria in this complex habitat seek to outcompete their neighbors for nutrients and eliminate competitors with antibacterial toxins ...
Ellen L. Zechner, Sabine Kienesberger
doaj   +1 more source

Lysophosphatidic Acid Signaling in the Gastrointestinal SystemSummary

Cellular and Molecular Gastroenterology and Hepatology
The intestinal epithelium undergoes continuous homeostatic renewal to conduct the digestion and absorption of nutrients. At the same time, the intestinal epithelial barrier separates the host from the intestinal lumen, preventing systemic infection from ...
C. Chris Yun, Yiran Han, Beth McConnell
doaj   +1 more source

Clonal and horizontal transmission of carbapenem-resistant Enterobacterales strains and genes via flies

Gut Pathogens
Background Antimicrobial resistance (AMR) is one of the most pressing global public health challenges; in particular, the rapid dissemination of carbapenem-resistant Enterobacterales (CRE) is emerging as a significant concern worldwide. Flies, serving as
Jialiang Xu, Jiaqi Liu, Jiayong Zhao, Tian Tian, Mengyu Wang, Gailing Yuan, Yao Peng, Yuan Zhang, Zhe Li, Biao Kan, Zhenpeng Li, Xin Lu   +11 more
doaj   +1 more source

The Progress and Promise of Lineage Reprogramming Strategies for Liver RegenerationSummary

Cellular and Molecular Gastroenterology and Hepatology
The liver exhibits remarkable regenerative capacity. However, the limited ability of primary human hepatocytes to proliferate in vitro, combined with a compromised regenerative capacity induced by pathological conditions in vivo, presents significant ...
Shuyong Wang, Xuan Wang, Yunfang Wang
doaj   +1 more source

A triad of gut dysbiosis, dysregulated immunity, and ‘leaky’ gut characterize HCMV associated neonatal cholestasis

Gut Pathogens
Background Gut microbiome dysbiosis and related immune dysfunction have been associated with the pathogenesis of Human Cytomegalovirus (HCMV) infection in infants with neonatal cholestasis (NC) as previously reported by us.
Kalyani Karandikar, Gauri Bhonde, Harsha Palav, Varsha Padwal, Shilpa Velhal, Jacintha Pereira, Himali Meshram, Akshat Goel, Ira Shah, Vainav Patel, Vikrant M. Bhor   +10 more
doaj   +1 more source