Results 31 to 40 of about 77,808 (100)

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2

New England Journal of Medicine, 2022
Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provides natural immunity against reinfection. Recent studies have shown waning of the immunity provided by the BNT162b2 vaccine. The time course of natural and hybrid
Y. Goldberg, Michael I. Mandel, Y. Bar-On, O. Bodenheimer, L. Freedman, N. Ash, S. alroy-Preis, A. Huppert, Ron Milo   +8 more
semanticscholar   +1 more source

Inflammation: Complexity and significance of cellular and molecular responses

Journal of Acute Disease
Inflammation is a multifaceted cellular and molecular response triggered by injury, infection, or various pathological conditions. Serving as a protective defense mechanism, the inflammatory response involves clinical signs like redness, swelling, pain ...
Serdar Özdemir
doaj   +1 more source

Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition.

New England Journal of Medicine, 2021
BACKGROUND Whether a broadly neutralizing antibody (bnAb) can be used to prevent human immunodeficiency virus type 1 (HIV-1) acquisition is unclear. METHODS We enrolled at-risk cisgender men and transgender persons in the Americas and Europe in the ...
L. Corey, P. Gilbert, M. Juraska, D. Montefiori, L. Morris, S. Karuna, Srilatha Edupuganti, N. Mgodi, Allan C. deCamp, Erika Rudnicki, Yunda Huang, P. Gonzales, R. Cabello, C. Orrell, J. Lama, F. Laher, E. Lazarus, Jorge Sanchez, I. Frank, J. Hinojosa, M. Sobieszczyk, Kyle Marshall, P. Mukwekwerere, J. Makhema, L. Baden, J. Mullins, C. Williamson, J. Hural, M. McElrath, Carter Bentley, Simbarashe Takuva, Margarita M Gomez Lorenzo, D. Burns, Nicole Espy, A. Randhawa, Nidhi Kochar, E. Piwowar-Manning, D. Donnell, N. Sista, P. Andrew, J. Kublin, G. Gray, J. Ledgerwood, J. Mascola, M. Cohen   +44 more
semanticscholar   +1 more source

Morphology-Based In-Ovo Sexing of Chick Embryos Utilizing a Low-Cost Imaging Apparatus and Machine Learning

Animals
Simple Summary In the laying hen industry, male chicks are typically killed after hatching because they have no economic value. This study developed a low-cost method to predict chick embryo sex before hatching by using a smartphone-based imaging device ...
Daniel Zhang, L. Jacobs
semanticscholar   +1 more source

Efficacy and safety of intravenous imatinib in COVID-19 ARDS: a randomized, double-blind, placebo-controlled clinical trial

Critical Care, 2023
Purpose A hallmark of acute respiratory distress syndrome (ARDS) is hypoxaemic respiratory failure due to pulmonary vascular hyperpermeability. The tyrosine kinase inhibitor imatinib reversed pulmonary capillary leak in preclinical studies and improved ...
Leila N. Atmowihardjo, Job R. Schippers, Erik Duijvelaar, Imke H. Bartelink, Pierre M. Bet, Noortje E. L. Swart, Nienke van Rein, Keith Purdy, David Cavalla, Andrew McElroy, Sarah Fritchley, Anton Vonk Noordegraaf, Henrik Endeman, Patricia van Velzen, Matty Koopmans, Harm Jan Bogaard, Leo Heunks, Nicole Juffermans, Marcus J. Schultz, Pieter R. Tuinman, Lieuwe D. J. Bos, Jurjan Aman   +21 more
doaj   +1 more source

Man against machine: diagnostic performance of a deep learning convolutional neural network for dermoscopic melanoma recognition in comparison to 58 dermatologists

Annals of Oncology, 2018
Background Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking. Methods Google's Inception v4 CNN architecture was trained
H. Haenssle, Christian Fink, R. Schneiderbauer, F. Toberer, T. Buhl, A. Blum, Aadi Kalloo, A. Hassen, L. Thomas, A. Enk, L. Uhlmann, C. Alt, M. Arenbergerova, R. Bakos, Anne Baltzer, I. Bertlich, A. Blum, Therezia Bokor-Billmann, J. Bowling, Naira Braghiroli, R. Braun, K. Buder-Bakhaya, T. Buhl, H. Cabo, L. Čabrijan, Naciye Cevic, A. Classen, David Deltgen, Christine Fink, I. Georgieva, L. Hakim-Meibodi, Susanne Hanner, Franziska Hartmann, J. Hartmann, G. Haus, E. Hoxha, R. Karls, H. Koga, J. Kreusch, A. Lallas, P. Majenka, A. Marghoob, C. Massone, L. Mekokishvili, D. Mestel, Volker Meyer, A. Neuberger, K. Nielsen, M. Oliviero, R. Pampena, J. Paoli, Erika Pawlik, B. Rao, Adriana Rendon, T. Russo, Ahmed Sadek, K. Samhaber, R. Schneiderbauer, A. Schweizer, F. Toberer, L. Trennheuser, Lyobomira Vlahova, Alexander Wald, J. Winkler, Priscila Wölbing, I. Zalaudek   +65 more
semanticscholar   +1 more source

Influence of gender on age-associated in-hospital mortality in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

Critical Care, 2023
Background Numerous epidemiological studies investigating gender-dependent clinical outcomes in sepsis have shown conflicting evidence. This study aimed to investigate the effect of gender on in-hospital mortality due to sepsis according to age group ...
Ryoung-Eun Ko, Danbee Kang, Juhee Cho, Soo Jin Na, Chi Ryang Chung, Sung Yoon Lim, Yeon Joo Lee, Sunghoon Park, Dong Kyu Oh, Su Yeon Lee, Mi Hyeon Park, Haein Lee, Chae-Man Lim, Gee Young Suh, the Korean Sepsis Alliance (KSA) investigators   +14 more
doaj   +1 more source

Antibody and T Cell Response to SARS-CoV-2 Messenger RNA BNT162b2 Vaccine in Kidney Transplant Recipients and Hemodialysis Patients

Journal of the American Society of Nephrology, 2021
Visual Abstract Significance Statement Antibody and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are poorly reported in kidney transplant recipients (KTRs) and patients on hemodialysis (HDPs). The authors
D. Bertrand, M. Hamzaoui, V. Lemée, Julie Lamulle, M. Hanoy, C. Laurent, Ludivine Lebourg, I. Étienne, Mathilde Lemoine, Frank Le Roy, D. Nezam, J. Plantier, O. Boyer, D. Guerrot, S. Candon   +14 more
semanticscholar   +1 more source

Sodium glucose co-transporter-2 inhibitors in intensive care unit patients with type 2 diabetes: a pilot case control study

Critical Care, 2023
Background Sodium glucose co-transporter-2 (SGLT2) inhibitors improve long-term cardiovascular and renal outcomes in individuals with type 2 diabetes. However, the safety of SGLT2 inhibitors in ICU patients with type 2 diabetes is uncertain.
Johan Mårtensson, Salvatore Lucio Cutuli, Eduardo A. Osawa, Fumitaka Yanase, Lisa Toh, Luca Cioccari, Nora Luethi, Akinori Maeda, Rinaldo Bellomo   +8 more
doaj   +1 more source

Prevalence of systemic venous congestion assessed by Venous Excess Ultrasound Grading System (VExUS) and association with acute kidney injury in a general ICU cohort: a prospective multicentric study

Critical Care, 2023
Background The importance of assessing venous congestion in ICU patients is widely acknowledged, but its study is hampered by the lack of a practical evaluation tool.
Stefan Andrei, Pierre-Alain Bahr, Maxime Nguyen, Belaid Bouhemad, Pierre-Grégoire Guinot   +4 more
doaj   +1 more source