Results 51 to 60 of about 77,808 (100)

Increasing angiotensin-converting enzyme concentrations and absent angiotensin-converting enzyme activity are associated with adverse kidney outcomes in pediatric septic shock

Critical Care, 2023
Background Sepsis-induced endothelial dysfunction is proposed to cause angiotensin-converting enzyme (ACE) dysfunction and renin–angiotensin–aldosterone system (RAAS) derangement, exacerbating vasodilatory shock and acute kidney injury (AKI). Few studies
Naomi Pode-Shakked, Giovanni Ceschia, James E. Rose, Stuart L. Goldstein, Natalja L. Stanski, the Genomics of Pediatric Septic Shock Investigators   +5 more
doaj   +1 more source

Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions

BMC Infectious Diseases, 2019
BackgroundThis study investigated the clinical value of interleukin-6 (IL-6), pentraxin 3 (PTX3), and procalcitonin (PCT) in patients with sepsis and septic shock diagnosed according to the Third International Consensus Definitions for Sepsis and Septic ...
Juhyun Song, D. Park, S. Moon, Hanjin Cho, Jong Hak Park, H. Seok, W. Choi   +6 more
semanticscholar   +1 more source

The impact of hypovolemia and PEEP on recirculation in venovenous ECMO: an experimental porcine model

Intensive Care Medicine Experimental
Background Recirculation is a common problem in venovenous extracorporeal membrane oxygenation (VV ECMO) and may limit the effect of ECMO treatment due to less efficient blood oxygenation or unfavorable ECMO and ventilator settings.
Lars Prag Antonsen, Andreas Espinoza, Per Steinar Halvorsen, Itai Schalit, Harald Bergan, Didrik Lilja, Svein Aslak Landsverk   +6 more
doaj   +1 more source

Characteristics of a trauma paediatric patient transported by emergency medical services: a retrospective analysis

Critical Care Innovations
INTRODUCTION: Injuries represent a widespread health problem worldwide and are the leading cause of both mortality and morbidity among children worldwide.
Mikołaj Domański, Aneta Michalczewska, Natalia Wierzejska, Barbara Kopczyńska, Mateusz Kopczyński, Tomasz Konieczny, Kaja Kubiak, Joanna Żyła, Jan Stachurski   +8 more
doaj   +1 more source

Incidence, characteristics, and prehospital outcomes of out-of-hospital cardiac arrest in Qatar: a nationwide gender-based investigation

International Journal of Emergency Medicine
Background Research on incidence and characteristics of Out-of-Hospital Cardiac Arrest (OHCA) in the Middle East is limited. We assessed the incidence, prehospital characteristics, and outcomes of OHCA in Qatar, a Middle Eastern country. Subsequently, we
Emad Awad, Hassan Farhat, Rakan Shami, Nooreh Gholami, Bothina Mortada, Niki Rumbolt, Adnaan Azizurrahman, Abdul Rahman Arabi, Guillaume Alinier   +8 more
doaj   +1 more source

Acute lung injury and post-cardiac arrest syndrome: a narrative review

Journal of Intensive Care
Background Post-cardiac arrest syndrome (PCAS) presents a multifaceted challenge in clinical practice, characterized by severe neurological injury and high mortality rates despite advancements in management strategies.
Yusuke Endo, Tomoaki Aoki, Daniel Jafari, Daniel M. Rolston, Jun Hagiwara, Kanako Ito-Hagiwara, Eriko Nakamura, Cyrus E. Kuschner, Lance B. Becker, Kei Hayashida   +9 more
doaj   +1 more source

Lactated Ringers, albumin and mannitol as priming during cardiopulmonary bypass reduces pulmonary edema in rats compared with hydroxyethyl starch

Intensive Care Medicine Experimental
Background Endothelial disorders with edema formation and microcirculatory perfusion disturbances are common in cardiac surgery with cardiopulmonary bypass (CPB) and contribute to disturbed tissue oxygenation resulting in organ dysfunction.
Anne M. Beukers, Anoek L. I. van Leeuwen, Roselique Ibelings, Anita M. Tuip-de Boer, Carolien S. E. Bulte, Susanne Eberl, Charissa E. van den Brom   +6 more
doaj   +1 more source

The relationship between immune status as measured by stimulated ex-vivo tumour necrosis factor alpha levels and the acquisition of nosocomial infections in critically ill mechanically ventilated patients

Intensive Care Medicine Experimental, 2020
Introduction Immunological dysfunction is common in critically ill patients but its clinical significance and the optimal method to measure it are unknown.
Gabrielle Levin, J. Gordon Boyd, Andrew Day, Miranda Hunt, David M. Maslove, Patrick Norman, Nicole O’Callaghan, Stephanie Sibley, John Muscedere   +8 more
doaj   +1 more source

The effect of neoadjuvant chemotherapy among patients undergoing radical cystectomy for variant histology bladder cancer: A systematic review. [PDF]

Arab J Urol, 2022
Alvarez-Maestro M, Chierigo F, Mantica G, Quesada-Olarte JM, Carrion DM, Gomez-Rivas J, Pinto-Marin A, Aguilera Bazan A, Martinez-Piñeiro L.   +8 more
europepmc   +1 more source

Angiotensin-(1–7) infusion in COVID-19 patients admitted to the ICU: a seamless phase 1–2 randomized clinical trial

Annals of Intensive Care
Background The coronavirus-related disease (COVID-19) is mainly characterized by a respiratory involvement. The renin-angiotensin system (RAS) has a relevant role in the pathogenesis of COVID-19, as the virus enters host’s cells via the angiotensin ...
Ana Luiza Valle Martins, Filippo Annoni, Filipe Alex da Silva, Lucas Bolais-Ramos, Gisele Capanema de Oliveira, Renata Cunha Ribeiro, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva, Beatriz Dias Pinheiro, Natália Abdo Rodrigues, Alana Helen dos Santos Matos, Daisy Motta-Santos, Maria José Campagnole-Santos, Thiago Verano-Braga, Fabio Silvio Taccone, Robson Augusto Souza Santos   +15 more
doaj   +1 more source