Results 161 to 170 of about 26,875 (312)

Clinical validation of a patient‐friendly saliva microsampling approach to monitor perampanel levels in people with epilepsy

Epilepsia, EarlyView.
Abstract Perampanel (PER) is a third‐generation antiseizure medication (ASM) with a well‐established concentration–effect relationship. Saliva represents a non‐invasive alternative to plasma for therapeutic drug monitoring (TDM) of PER, as it reflects the free plasma fraction.
Valentina Franco, Francesca Dattrino, Michela Palmisani, Federica Tacchella, Elena Tartara, Valentina De Giorgis, Carlo Alberto Quaranta, Ludovica Pasca, Paola Rota, Emilio Russo, Andrea Romigi, Cecilie Johannessen Landmark, Guido Fedele, Cristina Tassorelli, Pierluigi Nicotera   +14 more
wiley   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi, Jonathan Ipser, James T. Butler, Heath Pardoe, Hamid Soltanian‐Zadeh, Christian Rummel, Roland Wiest, Simon S. Keller, Barbara A. K. Kreilkamp, Anna Elisabetta Vaudano, Alice Ballerini, Stefano Meletti, Gerard Hall, Peter Taylor, Luis Concha, Alfonso Fajardo‐Valdez, Raphael Fernandes Casseb, Fernando Cendes, Clarissa L. Yasuda, Louis Lemieux, John S. Duncan, Esmaeil Davoodi‐Bodj, Orrin Devinsky, Sophia I. Thomopoulos, Dan J. Stein, Paul M. Thompson, Sanjay M. Sisodiya, Taha Gholipour, Carrie R. McDonald   +28 more
wiley   +1 more source

On‐site exposure to clinical epilepsy practice for experimental scientists engaged in epilepsy research: A pilot study by the ILAE commission on neurobiology

Epilepsia Open, EarlyView.
Abstract Educational initiatives that address the gap between basic/preclinical and clinical practices are important to effectively translate basic science discoveries to benefit patients. The ILAE Neurobiology Commission conducted a pilot project aimed at exposing basic and preclinical scientists engaged in epilepsy research to general clinical issues
Marco de Curtis, Giulia Battaglia, Gustavo Aguado‐Carrillo, Eleonora Aronica, Melody Asukile, Simona Balestrini, Carmen Barba, Tobias Baumgartner, Albert J. Becker, Francesca Bisulli, Patricia Braga, Nihan Carcak, Esper Cavalheiro, Norman Delanty, Lorenzo Ferri, Alon Friedman, Daniel Friedman, Marian Galovic, Jennifer N. Gelinas, Brenda Giagante, Rodrigo Henriquez‐Ch, Veena Kander, Silvia Kochen, David Krysl, Martin Kudr, Akio Ikeda, Mariana Legnani, Yicong Lin, Iris Martinez‐Juarez, Lorenzo Muccioli, Naluca Mwendaweli, Silvia Oddo, Çigdem Özkara, Jose Eduardo Peixoto‐Santos, Piero Perucca, Heidrun Potschka, Luisa Rocha, Helen Scharfman, Ingrid E. Scheffer, Rainer Surges, Chanez Charfi Triki, Reinaldo Uribe‐San‐Martin, Kette Valente, Erwin A. van Vliet, Yuping Wang, Benjamin Whatley, Jo M. Wilmshurst, Elza Marcia Yacubian, Alessandro De Rossi, Stefano de Curtis, Premysl Jiruska, David C. Henshall   +51 more
wiley   +1 more source

Sensitivity of 3D Base‐Isolated Buildings to Individual Isolator Variability

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Variability in elastomeric isolators arises from differences in rubber formulation and curing, leading to noticeable changes in stiffness and damping among nominally identical bearings. While most previous studies have examined global isolator variability associated with environmental or aging effects, individual isolator variability has ...
Norouz Jahan, Niel C. Van Engelen
wiley   +1 more source

Applied Element Modelling of Out‐Of‐Plane Instability in Boundary Elements of Thin RC Walls

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Recent earthquakes in Chile (2010) and New Zealand (2011) caused extensive damage to buildings featuring reinforced concrete (RC) structural walls, with observed failure modes including out‐of‐plane instability of slender walls. This buckling‐type response under combined in‐plane and out‐of‐plane loading has also been documented in ...
Andrea Orgnoni, Rui Pinho, João Pacheco de Almeida   +2 more
wiley   +1 more source

Corrosion of RC Columns Repaired and Wrapped with CFRP Sheets

, 2006
This study aimed to investigate how effectively CFRP sheet performs on inhibiting the corrosion process of steel reinforcements embedded in RC columns.
Bae, S., Belarbi, Abdeldjelil
core  

Integrated NSM and GFRP-reinforced ECC/UHPC techniques for strengthening deficient RC columns. [PDF]

Sci Rep
Elsamak G, Bahrami A, Emara M, Mahfouz YMB, Iskander Y, Ghalla M.   +5 more
europepmc   +1 more source

Empirical Model of Post‐Earthquake Restoration Time for Building Components Based on Data From the 2022 Fukushima‐ken Oki Earthquake in Japan

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Estimation of the time required for damaged building components to return to their pre‐earthquake conditions through repair is a critical element in assessing the seismic resilience of buildings, and it requires consideration of uncertainty.
Tomoaki Nishino, Takeshi Morii, Rie Okazawa, Hiroaki Notake, Aya Hada, Takahiro Matsui   +5 more
wiley   +1 more source

Shear and Flexural Behavior of RC Columns with Rectangular Hollow Cross-Sections Under Cyclic Loading. [PDF]

Materials (Basel)
Jin K, Choi H, Quan C.
europepmc   +1 more source

Repeatability and Parasitic Out‐of‐Plane Motion in Controlled Rocking Structures With Cylindrical Columns: Results From Triaxial Shake Table Tests

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Self‐centering rocking structures outperform conventional ones since they show zero post‐earthquake damage and excellent recentering; however, their applications remain limited due to concerns that rocking is extremely sensitive and nonrepeatable. This paper investigates the repeatability and parasitic out‐of‐plane motion of controlled rocking
Antonios A. Katsamakas
wiley   +1 more source