Results 181 to 190 of about 75,178 (253)

Prostaglandin E2 (PGE2) signaling regulates fluid excretion and uric acid metabolism in the mosquito Anopheles gambiae

open access: yesInsect Science, EarlyView.
Prostaglandin E2 (PGE2) signaling via its receptor has integral roles in mosquito physiology, mediating fluid excretion, stimulating hindgut contractions, and in modulating uric acid levels. Together, these results uncover previously unrecognized roles of prostaglandin signaling in osmotic balance and metabolic homeostasis in mosquitoes.
Hyeogsun Kwon   +3 more
wiley   +1 more source

Prophylactic Cranial Irradiation Versus Active MRI Surveillance in Small Cell Lung Cancer: Systematic Review and Meta‐Analysis

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Background Prophylactic cranial irradiation (PCI) has traditionally been a cornerstone of treatment in limited‐stage and extensive‐stage small cell lung cancer (SCLC). Recent evidence suggests that active MRI brain surveillance may result in comparable overall survival (OS) and progression‐free survival (PFS).
Zhao Feng Liu   +7 more
wiley   +1 more source

Genotyping Contemporary Captive and Historical Wild Western Lowland Gorillas Indicates Captive Breeding Is Maintaining Genetic Diversity in a Critically Endangered Primate

open access: yesAnimal Conservation, EarlyView.
Captive populations of threatened species risk losing genetic diversity over time. We evaluated the genetic status of contemporary captive western lowland gorillas (Gorilla gorilla gorilla) at Howletts and Port Lympne and compared this with specimens from a historical wild population.
Jaimie Morris   +5 more
wiley   +1 more source

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil   +3 more
wiley   +1 more source

Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang   +6 more
wiley   +1 more source

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