Results 11 to 20 of about 140,078 (149)

Sense of smell in chronic rhinosinusitis: A multicentric study on 811 patients

Frontiers in Allergy, 2023
Introduction The impairment of the sense of smell is often related to chronic rhinosinusitis (CRS) with or without nasal polyps (CRSwNP, CRSsNP). CRSwNP is a frequent condition that drastically worsens the quality of life of those affected; it has a ...
A. Macchi, A. Giorli, E. Cantone, Giorgia Carlotta Pipolo, F. Arnone, Umberto Barbone, G. Bertazzoni, C. Bianchini, A. Ciofalo, Federica Cipolla, Alessio De Massimi, Carla De Vita, Cristina Di Lieto, A. Ghidini, M. Govoni, G. Gramellini, Alessandro Maselli del Giudice, G. Ottaviano, V. Seccia, F. Sireci, G. Sollini, C. Staffieri, S. Gallo, E. Heffler, I. Mantia, Eugenio de Corso, F. R. Canevari, N. Lombardo, L. Malvezzi, Gabriele Orietti, E. Pasquini, L. Presutti, G. Monti   +32 more
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The Phosphoproteome of the Rd1 Mouse Retina, a Model of Inherited Photoreceptor Degeneration, Changes after Protein Kinase G Inhibition

International Journal of Molecular Sciences, 2023
Retinitis pigmentosa (RP) is a frequent cause of blindness among the working population in industrial countries due to the inheritable death of photoreceptors. Though gene therapy was recently approved for mutations in the RPE65 gene, there is in general
Jia-mei Zhou, C. Welinder, P. Ekström
semanticscholar   +1 more source

Nanosecond Laser Annealing of NMC 811 Cathodes for Enhanced Performance

Journal of the Electrochemical Society, 2023
Improved performance of LIBs plays a critical role in the future of next- generation battery applications. Nickel-rich layered oxides such as LiNi0.8Mn0.1Co0.1O2 (NMC 811), are popular cathodes due to their high energy densities.
Nayna Khosla, J. Narayan, R. Narayan, Xiao-Guang Sun, M. Paranthaman   +4 more
semanticscholar   +1 more source

Morphology and Particle Size of a Synthesized NMC 811 Cathode Precursor with Mixed Hydroxide Precipitate and Nickel Sulfate as Nickel Sources and Comparison of Their Electrochemical Performances in an NMC 811 Lithium-Ion Battery

Energies, 2022
Cathode precursors of lithium-NMC 811 were synthesized by the coprecipitation method using two different nickel sources, namely mixed nickel–cobalt hydroxide precipitate (MHP) and nickel sulfate.
A. S. Wijareni, H. Widiyandari, A. Purwanto, A. F. Arif, M. Z. Mubarok   +4 more
semanticscholar   +1 more source

Surface Coating of NCM-811 Cathode Materials with g-C3N4 for Enhanced Electrochemical Performance

ACS Omega, 2022
Li(Ni0.8, Co0.1, Mn0.1)O2 (NCM-811) cathode materials have been commercialized recently, aiming to increase the specific capacity and specific energy of the lithium-ion battery for practical applications in electric vehicles. The surface coating has been
Sheng-Xiong She, Yang-Liu Zhou, Zijian Hong, Yuhui Huang, Yongjun Wu   +4 more
semanticscholar   +1 more source

Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration

International Journal of Molecular Sciences, 2022
Retinitis pigmentosa (RP) is a group of inherited retinal dystrophies that typically results in photoreceptor cell death and vision loss. Here, we explored the effect of early growth response-1 (EGR1) expression on photoreceptor cell death in Pde6brd1 ...
Yujie Dong, Wenrong Xu, Yan Li, Chun-jiang Wei, Yunzhang Hu, Z. Hu, F. Paquet-Durand, K. Jiao   +7 more
semanticscholar   +1 more source

Multi-omics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration.

Human Molecular Genetics, 2022
Retinal diseases exhibit extensive genetic heterogeneity and complex etiology with varying onset and severity. Mutations in over 200 genes can lead to photoreceptor dysfunction and/or cell death in retinal neurodegeneration.
Ke Jiang, A. Mondal, Yogita K Adlakha, Jessica D. Gumerson, A. Aponte, L. Gieser, Jung-Woong Kim, Alexis Boleda, M. Brooks, Jacob Nellissery, D. Fox, R. Balaban, R. Covian, A. Swaroop   +13 more
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Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

Investigative Ophthalmology and Visual Science, 2021
Purpose Oxidative stress is a major factor underlying many neurodegenerative diseases. However, antioxidant therapy has had mixed results, possibly because of its indiscriminate activity. The purpose of our study was to determine if the human OXR1 (hOXR1)
Bhubanananda Sahu, Laura Moreno Leon, Wei Zhang, Nikita Puranik, R. Periasamy, H. Khanna, M. Volkert   +6 more
semanticscholar   +1 more source

Inhibition of mTOR signaling by rapamycin protects photoreceptors from degeneration in rd1 mice

Zoological Research, 2021
Retinitis pigmentosa (RP) is an inherited retinal degenerative disease that begins with defective rod photoreceptor function, followed by impaired cone function, and complete blindness in its late stage.
Jialiang Yang, Tongdan Zou, Fang Yang, Zhenglin Yang, Houbin Zhang   +4 more
semanticscholar   +1 more source

The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia–reperfusion in vivo

Scientific Reports, 2021
Acute ischemia–reperfusion injury in skeletal muscle is a significant clinical concern in the trauma setting. The mitochondrial permeability transition inhibitor NIM-811 has previously been shown to reduce ischemic injury in the liver and kidney.
Khairat Bahgat Youssef El Baradie, M. Khan, B. Mendhe, J. Waller, F. O'Brien, M. Hamrick   +5 more
semanticscholar   +1 more source