Results 31 to 40 of about 151,952 (148)

Inhibition of mTOR signaling by rapamycin protects photoreceptors from degeneration in rd1 mice

Zoological Research, 2021
Retinitis pigmentosa (RP) is an inherited retinal degenerative disease that begins with defective rod photoreceptor function, followed by impaired cone function, and complete blindness in its late stage.
Jialiang Yang, Tongdan Zou, Fang Yang, Zhenglin Yang, Houbin Zhang   +4 more
semanticscholar   +1 more source

The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia–reperfusion in vivo

Scientific Reports, 2021
Acute ischemia–reperfusion injury in skeletal muscle is a significant clinical concern in the trauma setting. The mitochondrial permeability transition inhibitor NIM-811 has previously been shown to reduce ischemic injury in the liver and kidney.
Khairat Bahgat Youssef El Baradie, M. Khan, B. Mendhe, J. Waller, F. O'Brien, M. Hamrick   +5 more
semanticscholar   +1 more source

First-line pembrolizumab/placebo plus trastuzumab and chemotherapy in HER2-positive advanced gastric cancer: KEYNOTE-811

Future Oncology, 2020
Treatment options for patients with HER2-positive advanced gastric cancer are limited, and the prognosis for these patients is poor. Pembrolizumab has demonstrated promising antitumor activity in patients with advanced gastric or gastroesophageal ...
H. Chung, Y. Bang, Charles S Fuchs, S. Qin, T. Satoh, K. Shitara, J. Tabernero, E. Cutsem, M. Alsina, Z. Cao, Jia Lu, P. Bhagia, C. Shih, Y. Janjigian   +13 more
semanticscholar   +1 more source

Comparative analysis of the degree of patient satisfaction after breast-conserving surgery with or without oncoplastic surgery: systematic review and meta-analysis

Frontiers in Surgery
IntroductionConservative surgery is the gold standard for the treatment of single and small tumors and, combined with the concept of oncoplastic tumors, brings good aesthetic results while maintaining cancer safety.
Fabiana Christina Araújo Pereira Lisboa, Lucimara Priscila Campos Veras Giorgi, Ana Claudia Morais Godoy Figueiredo, Régis Resende Paulinelli, João Batista de Sousa   +4 more
doaj   +1 more source

Long-Term Cyclability of NCM-811 at High Voltages in Lithium-Ion Batteries: an In-Depth Diagnostic Study

, 2020
High-nickel layered oxides, such as LiNi0.8Co0.1Mn0.1O2 (NCM-811), offer higher energy density than their low-nickel counterparts at a given voltage and are gaining major traction in automotive lit...
Wangda Li, Xiaoming Liu, Q. Xie, Ya You, M. Chi, A. Manthiram   +5 more
semanticscholar   +1 more source

Myositis ossificans traumatica of masticatory muscles: A case report and review of the literature

Oral and Maxillofacial Surgery Cases
Myositis ossificans traumatica (MOT) is a rare condition characterized by nonneoplastic, heterotopic bone formation in the masticatory muscles following acute trauma.
Amir Jalal Abbasi, Mohammad Mehdi Taheri, Amirali Asadi, Rashin Bahrami, Nariman Nikparto   +4 more
doaj   +1 more source

The temporal progression of retinal degeneration and early-stage idebenone treatment in the Pde6brd1/rd1 mouse model of retinal dystrophy

Scientific Reports
Photoreceptor cell death, primarily through apoptosis, related to retinal disorders like retinitis pigmentosa (RP), would result in vision loss. The pathological processes and crucial mutant conditions preceding photoreceptor cell demise are not well ...
Lei Zhang, Wei Liu, Haiyan Wang, Wei Qiang, Ru Wang, Zhi-Li Cui, Zuo-Ming Zhang   +6 more
semanticscholar   +1 more source

Bacterial profile and antibiotic susceptibility patterns in patients with secondary peritonitis: a cross-sectional study in Uganda

Perioperative Medicine
Introduction Secondary peritonitis is the second leading cause of sepsis worldwide. Drug resistance to peritoneal cavity bacterial infection remains a public health threat, especially in resource-limited settings in Africa, including Uganda.
Nyenke Bassara Godefroy, Joshua Muhumuza, Selamo Fabrice Molen, Musa Abbas Waziri, ByaMungu Pahari Kagenderezo, Bienfait Mumbere Vahwere, Frank Katembo Sikakulya, William Mauricio, Joel Wandabwa, Bisingurege Kagoro Francois, Ezera Agwu, Xaviour Francis Okedi   +11 more
doaj   +1 more source

In vitro Antibacterial Activity of Ethanolic Tanao Si Kan Dang RD1 (Cannabis sativa L.) Extracts Against Human Antibiotic-Resistant Bacteria.

Pakistan Journal of Biological Sciences
Background and Objective: A new strain of cannabis, Cannabis sativa L. Tanao Si Kan Dang RD1, has been approved and registered by the Rajamangala University of Technology Isan, Thailand. The C.
Nipaporn Armassa, Duanpen Wongsorn, Benya Saenmahaya, S. Rayan, S. Rattanasuk   +4 more
semanticscholar   +1 more source

The efficacy of 3D gait analysis to evaluate surgical (and rehabilitation) outcome after degenerative lumbar surgery

BMC Surgery
Background Lumbar degenerative conditions are a major cause of back pain and disability in individuals aged 45 and above. Gait analysis utilizes sensor technology to collect movement data, aiding in the evaluation of various gait aspects like ...
Chao Zhou, Ning Zhou, Yanping Zheng, Haipeng Si, Yanguo Wang, Jun Yin   +5 more
doaj   +1 more source