Results 51 to 60 of about 141,935 (149)

Avaliação do fluxo arterial mesentérico em humanos durante o exercício

Revista do Colégio Brasileiro de Cirurgiões
O aumento da atividade simpática durante o exercício dinâmico progressivo associa-se à resposta da concentração de lactato sangüíneo. Com o objetivo de testar a hipótese de que a diminuição do fluxo da artéria mesentérica superior também tenha relação ...
Adamastor Humberto Pereira, Júlio Lewis Nectoux Filho, Emil Burihan, Jorge Pinto Ribeiro, Marcos Braun Burger, Sérgio Ricardo Araújo de Moraes   +5 more
doaj   +1 more source

Spatio-temporal characterization of S- and M/L-cone degeneration in the Rd1 mouse model of retinitis pigmentosa

BMC Neuroscience, 2019
The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments.
Daniel S Narayan, J. Ao, J. Wood, R. Casson, G. Chidlow   +4 more
semanticscholar   +1 more source

Papillary neoplasias of the biliary tract

Revista do Colégio Brasileiro de Cirurgiões
The authors conducted a revisional study of intraepithelial papillary lesions of the bile ducts, characterized by being a kind of rare, intraductal growing cholangiocarcinoma. Articles published in the last 10 years were reviewed.
Vivian Resende, João Paulo Lemos da Silveira Santos, Rodrigo Vieira Gomes, Paula Vieira Teixeira Vidigal, Moisés Salgado Pedrosa   +4 more
doaj   +1 more source

DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice

Cell Death and Disease, 2018
Retinitis pigmentosa (RP) is a group of inherited retinal degenerative diseases causing progressive loss of photoreceptors. Numerous gene mutations are identified to be related with RP, but epigenetic modifications may also be involved in the ...
Shijie Zheng, Lirong Xiao, Yu Liu, Yujiao Wang, Lin Cheng, Junjun Zhang, Naihong Yan, Danian Chen   +7 more
semanticscholar   +1 more source

Lycium Barbarum Polysaccharides Protect Retina in rd1 Mice During Photoreceptor Degeneration

Investigative Ophthalmology and Visual Science, 2018
Purpose As an active component in wolfberry, lycium barbarum polysaccharides (LBP) are capable of protecting retinal neurons in several animal disease models.
Feng Liu, Jia Zhang, Zongqin Xiang, Di Xu, K. So, N. Vardi, Ying Xu   +6 more
semanticscholar   +1 more source

Discovering Jewish Studies Collections in Academic Libraries: A Practical Guide

, 2014
The U.S. colleges and universities offering non-sectarian educational programs in Jewish Studies rely on the support of their academic libraries for research materials and library services.
Taler, Izabella
core  

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

Gene Therapy, 2017
There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery—intravitreal or subretinal.
Doron G Hickey, T. L. Edwards, A. Barnard, Mandeep S. Singh, Mandeep S. Singh, S. R. D. Silva, M. McClements, J. Flannery, M. Hankins, R. MacLaren, R. MacLaren   +10 more
semanticscholar   +1 more source

Peripheral blood-derived monocytes show neuronal properties and integration in immune-deficient rd1 mouse model upon phenotypic differentiation and induction with retinal growth factors

Stem cell research & therapeutics, 2020
Background Cell therapy is one of the most promising therapeutic interventions for retinitis pigmentosa. In the current study, we aimed to assess if peripheral blood-derived monocytes which are highly abundant and accessible could be utilized as a ...
Alaknanda Mishra, K. V. Mohan, P. Nagarajan, S. Iyer, Ashwani Kesarwani, Madhu Nath, Laxmi Moksha, Jashdeep Bhattacharjee, Barun Das, K. Jain, P. Sahu, Prakriti Sinha, T. Velapandian, P. Upadhyay   +13 more
semanticscholar   +1 more source

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Arthritis & Rheumatology, 2017
Interferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE.
V. Werth, D. Fiorentino, B. Sullivan, M. Boedigheimer, Kit Chiu, Christine Wang, G. E. Arnold, M. Damore, J. Bigler, A. Welcher, C. Russell, David A. Martin, J. Chung   +12 more
semanticscholar   +1 more source

The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer

Nature, 2021
Y. Janjigian, A. Kawazoe, P. Yanez, Ning Li, S. Lonardi, O. Kolesnik, O. Barajas, Y. Bai, L. Shen, Yong Tang, L. Wyrwicz, Jianming Xu, K. Shitara, S. Qin, E. Van Cutsem, J. Tabernero, Lie Li, Sukrut Shah, P. Bhagia, H. Chung   +19 more
semanticscholar   +1 more source