Results 271 to 280 of about 159,821 (315)

Hematopoietic effects of tagraxofusp in treatment‐naive patients with blastic plasmacytoid dendritic cell neoplasm

open access: yesCancer, Volume 132, Issue 1, 1 January 2026.
Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN), an aggressive hematologic neoplasm that expresses CD123, is often observed in the bone marrow (BM), as well as skin, blood, and viscera. Tagraxofusp, a first‐in‐class CD123‐targeted therapy, is the only drug approved to treat BPDCN.
Marina Konopleva   +10 more
wiley   +1 more source

Clinical prediction of aortic arch anatomy to guide stroke CT angiography protocols: A machine learning study. [PDF]

open access: yesNeuroradiol J
Marquez-Romero JM   +4 more
europepmc   +1 more source

Electrochemical Detection of SARS‐CoV‐2 in Saliva Using ZnO Nanorods Functionalized with Gold‐Conjugated Antireceptor‐Binding Domain Antibodies

open access: yesChemNanoMat, Volume 12, Issue 1, January 2026.
An electrochemical immunosensor based on ZnO nanorods functionalized with gold nanoparticle‐conjugated anti‐receptor‐binding domain antibodies enables rapid, noninvasive, and selective detection of SARS‐CoV‐2 in saliva, providing a promising platform for point‐of‐care diagnostic applications.
Fabíola Lelis de Castro   +15 more
wiley   +1 more source

GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 74-79, January 2026.
Pharmacogenomics enables the personalization of drug therapy by linking genetic variations to differences in drug metabolism, efficacy, and risk of adverse reactions. Genetic polymorphisms within cytochrome P450 (CYP) genes significantly affect enzyme activity, influencing drug plasma levels, responses, and safety.
Alex J. Coulter   +4 more
wiley   +1 more source

Linking oceanic variability, euphausiid hotspot persistence, and marine predator distribution along Canada's west coast

open access: yesEcological Applications, Volume 36, Issue 1, January 2026.
Abstract Understanding patterns of habitat use across trophic levels and the physical drivers of multispecies aggregations is essential to inform ecosystem‐based management. To achieve this, we quantified the spatial distribution and co‐occurrence of hotspots (defined using the Getis‐Ord statistic) for euphausiids and nine of their commercially ...
Rhian Evans   +6 more
wiley   +1 more source

Deterministic and Stochastic Processes Regulate Co‐Occurrence Network Structure and Shape Macroinvertebrate Diversity in Karst Environment

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
Keystone taxa and co‐occurrence network modules are fundamental basis for maintaining biodiversity in macroinvertebrate communities. Modules enhance interactions among macroinvertebrates and promote species coexistence which further influences diversity.
Wei Liu   +3 more
wiley   +1 more source

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