Results 71 to 80 of about 13,237 (236)
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
British Journal of Haematology, EarlyView.Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source
¿Colapso u orden? Cuestionando el colapso del estado en África
Relaciones Internacionales, 2008 Tras el 11 de septiembre, el problema del “colapso” del estado aparece una vez más en la agenda como una cuestión importante de seguridad global. Sinembargo, la discusión académica no ha ido mucho más allá de la injerencia en las dinámicas postconflicto ...
Timothy RAEYMAEKERS
doaj
British Journal of Pharmacology, EarlyView.NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness +21 more
wiley +1 more source
Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2020 En vue d’identifier les trypanosomes circulants chez les animaux domestiques de Kinshasa, Mbanza-Ngungu, Masi-Manimba et Mushie et d’en déterminer les prévalences par PCR, une étude longitudinale a été menée.
Willy KABAMBA MWAMBA +5 more
doaj
Fertility incentives in Canada: Period and cohort perspectives
Canadian Journal of Economics/Revue canadienne d'économique, EarlyView.Abstract We study the fertility effects of the 1997 Quebec Family Policy using two complementary approaches: (i) a period‐based repeated cross‐sectional analysis that examines the impact on period fertility (i.e., fertility rates in a given calendar year, such as births per 1,000 women age 15 to 49), and (ii) a cohort‐based panel analysis that examines
Siha Lee, Sitian Liu
wiley +1 more source
Frontiers in EndocrinologyBackgroundOleoylethanolamide (OEA) is an endogenous lipid mediator involved in nutrient sensing and gut-derived hormonal signalling. TRPTI™ is a bioavailable OEA formulation designed to support metabolic and appetite-related pathways.
David Briskey +3 more
doaj +1 more source
Impact of after‐school care on maternal income: Evidence from Canadian administrative data
Canadian Journal of Economics/Revue canadienne d'économique, EarlyView.Abstract This paper estimates the average causal effect of access to subsidized before‐ and after‐school care on the labour market outcomes of mothers. Specifically, we analyze a major policy reform implemented in Quebec (Canada) in 1998, which required all public primary schools to provide before‐ and after‐school care at a low fixed fee, thereby ...
Ailin He, Laetitia Renée, Nagham Sayour
wiley +1 more source
Temporomandibular joint disorder and gross motor function in children with cerebral palsy
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To determine the prevalence of the clinical signs and symptoms of temporomandibular joint (TMJ) disorder (TMD) in children with cerebral palsy (CP) and to examine their associations with severity of gross motor impairment, CP subtype, and caregiver‐reported bruxism. Method This cross‐sectional study included 517 children with CP (mean age =
Özge Baykan Çopuroğlu +2 more
wiley +1 more source
Dynamique transfrontalière Rwanda-RDC
, 2020 Cette note stratégique résume les considérations clés inhérentes à la dynamique transfrontalière entre le Rwanda et la République démocratique du Congo (RDC) dans le contexte de la flambée épidémique d’Ébola survenue dans les provinces du Nord-Kivu et de l’Ituri.
Lamarque, Hugh +2 more
openaire +1 more source