Results 41 to 50 of about 9,675 (200)

DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity

International Journal of Cancer, EarlyView.
Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin   +12 more
wiley   +1 more source

The role of the support of top management in gender equality outcomes in higher education and research

Feminismo/s
In the past decade, there has been increasing attention globally to the institutionalisation of diversity management practices in research, development and innovation (RDI) organisations, as well as the necessity of addressing more effectively various ...
Katalin Tardos, Veronika Paksi
doaj   +1 more source

Drought Risk in Mango and Avocado Orchards: Insights Into Plant Water Relations and Irrigation‐Related Agronomic Solutions

Irrigation and Drainage, EarlyView.
ABSTRACT Climate change is making water availability more uncertain, with growing consequences for the productivity and long‐term sustainability of tropical and subtropical fruit orchards. Mangifera indica L. and Persea americana Mill. both require large amounts of water to sustain growth and productivity.
Eleonora Cataldo
wiley   +1 more source

Research, development and innovation in business enterprises: experience from Egypt

Insights into Regional Development, 2023
This paper addresses the linkages between research and development (R&D) and innovation on the one hand and the socioeconomic impact of research, development and innovation (RDI) on the other hand.
Motaz Khorshid, Mohamed Ramadan A. Rezk, Mohamed Ismail, Leonardo Piccinetti, Amr Radwan, Omneia Helmy, Mahmoud M. Sakr   +6 more
doaj   +1 more source

Maxillomandibular Advancement Outcomes in Obstructive Sleep Apnea by Age and Gender

The Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 36 studies (608 patients) found that maxillomandibular advancement significantly improves polysomnographic, cephalometric, and subjective measures of obstructive sleep apnea across both sexes and throughout the lifespan. Odds of surgical cure decline roughly 3% per year of age.
Matthew O. Herbst, Lucas C. Licaj, Ethan M. Kallenberger, Shaun A. Nguyen, Courtney Chou, Allen Huang, Emily A. Brennan, Mohamed Abdelwahab   +7 more
wiley   +1 more source

Understanding the manifold approaches that shape research, development and innovation policies

TalTech Journal of European Studies
This study examines the intersection of intellectual property (IP) law, social systems theory and ethical considerations in shaping sustainable research, development and innovation (RDI) policies.
Dutt Pawan Kumar, Chochia Archil, Hoffmann Thomas   +2 more
doaj   +1 more source

Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay

Cancer Treatment and Research Communications, 2021
Background: The study investigated the association of the relative dose-intensity (RDI) of cisplatin and timing of adjuvant platinum-based chemotherapy (APC) with survival for stage I-III non-small cell lung cancer (NSCLC) patients. Material and Methods:
WM Szejniuk, M Cekala, M Bøgsted, C Meristoudis, T McCulloch, UG Falkmer, OD Røe   +6 more
doaj   +1 more source

Social‐ecological sustainability of olive farming in the Mediterranean: A review of current practices and an agroecological perspective

People and Nature, EarlyView.
Abstract Olive farming represents a prime example of a biodiversity‐rich land‐use system in the Mediterranean, deeply rooted in a long history and cultural traditions, yet it faces mounting challenges from climate change, biodiversity loss, and declining economic viability that put its sustainability at risk.
Klara Dietrich, Claudia Bieling, Corrado Ciaccia, Ingo Grass   +3 more
wiley   +1 more source

Harnessing the nutritional potential of Cape wild edible plants: Insights, gaps and priorities

PLANTS, PEOPLE, PLANET, EarlyView.
Wild edible plants hold significant potential to strengthen food systems by enhancing nutrition, dietary diversity, climate resilience, sustainability and deeper connection of people to their food. In this study, we conducted a systematic literature review to identify knowledge gaps and assess the nutritional contributions of selected wild edible ...
Nicola Kühn, Loubie Rusch, Michelle Delport, Frances Storey, Emma van der Meulen, Laura Pereira   +5 more
wiley   +1 more source

Meteorological drought assessment using SPI and RDI indices in the Ourika Basin, Morocco [PDF]

E3S Web of Conferences
The Ourika basin is located on the northern edge of the Marrakech High Atlas, within a semi-arid to sub-humid climate. Its fragile natural environment is exposed to extreme and harsh climatic conditions, such as droughts and floods.
Khrabcha Abdelali, Oumou Abdellah, Essahlaoui Ali, Essahlaoui Narjisse, Kassou Amina, Mouzoun Ouafae, Alitane Abdennabi, El Hafyani Mohammed, Iharzi Chaimae, Van Rompaey Anton   +9 more
doaj   +1 more source