Results 221 to 230 of about 86,065 (262)
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Immunogenicity of rDNA-derived pharmaceuticals

Trends in Pharmacological Sciences, 2002
Many biopharmaceuticals have been reported to induce the production of antibodies. Several factors influence immunogenicity, including the methods of production, formulation and storage as well as patient characteristics (e.g. type of disease and genetic background).
Ryff, J.C., Schellekens, H.
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Initiation of transcription of rDNA in rice

Biochemical and Biophysical Research Communications, 1989
Three direct repeats of 320, 340 and 238 nucleotides were detected upstream to the 5' end of the 18S rRNA gene of an rDNA unit present on a 9.8 kb EcoRI fragment of the rice DNA. The primer extension analysis showed that the site of initiation of transcription is in the 1st repeat at an A, the 623rd nucleotide upstream to the 5' end of the 18S rRNA ...
Nandabalan, K, Padayatty, JD
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Chromosomal localization of rDNA in the Brassicaceae

Genome, 2005
A survey is given about the number and chromosomal position of rDNA loci in 45 Brassicaceae species. For 34 species, 5S and 45S rDNA loci have been localized by two-colour fluorescence in situ hybridization for the first time. These data show the variability of rDNA within karyotypes of the Brassicaceae, provide anchor points for (comparative) genetic
Hoda B M, Ali   +2 more
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The study of a rDNA replicator in Saccharomyces

Current Genetics, 1983
We have previously demonstrated that the loss of Rcp-CEN3, a centromeric plasmid containing yeast rDNA autonomously replicating sequences (ARS) is as high as around 50% per generation for most yeast strains. In this study we have attempted to elucidate mechanisms underlying the high mitotic instability of Rcp-CEN3. For this purpose a tandem duplication
N Y, Kouprina, V L, Larionov
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Visualizing human 5S rDNA

Chromosome Research, 1997
[No abstract available]
PELLICCIA, Franca   +3 more
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rDNA and acrocentric chromosomes in man

Cell Differentiation, 1974
A malformed female infant was found to have a 46,XX complement with a chromosome 8 shorter than normal with a secondary constriction and satellites on the short arm. Chromosome studies on the clinically normal father showed a balanced translocation between chromosome 8 and 13, i.e., 46,XY,t(8;13) (p21 p12). The proposita, carrier of the unbalanced form
G, Guanti, P, Petrinelli
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Phylogeny of Hesionidae (Aciculata, Polychaeta), assessed from morphology, 18S rDNA, 28S rDNA, 16S rDNA and COI

Zoologica Scripta, 2006
We assess phylogenetic relationships within the polychaete family Hesionidae from morphological data combined with nucleotide data from 18S rDNA, 28S rDNA, 16S rDNA and COI. Parsimony and Bayesian analyses were performed on two data sets; the first was based on a more restricted set of terminals with both morphological and molecular data (17 ingroup ...
Christine Ruta   +6 more
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The Dictyostelium discoideum 5S rDNA Is Organized in the Same Transcriptional Orientation as the Other rDNAs

Biochemical and Biophysical Research Communications, 1993
In eukaryotes 5S rRNA genes are transcribed by RNA polymerase III. These genes occur in D. discoideum on the ca. 90 copies of an extrachromosomal palindrom together with the other ribosomal RNAs, which are generally transcribed by RNA polymerase I. A 5S rRNA gene has been isolated and its nucleotide sequence as well as the organization of the gene ...
J, Hofmann   +6 more
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rDNA magnification in D. melanogaster: State of rDNA copies following the first step

Molecular and General Genetics MGG, 1979
D. melanogaster males of XYbb/O genetic constitution undergoing rDNA magnification were mated singly to XXbb+/O females, yielding XYbb/O male progeny, and to XNO- w sn bb+ females, yielding XYbb/XNO- females. The male and female offspring were scored for the bb+ phenotype.
Graziani F, LA MANTIA, GIROLAMA
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Molecular structure of the rDNA intergenic spacer (IGS) in Triturus: implications for the hypervariability of rDNA loci

Chromosoma, 1997
Ribosomal DNA (rDNA) variation in the species Triturus vulgaris meridionalis (Amphibia, Urodela) is remarkable because of unusually high intraspecific variability in the number and distribution of ribosomal loci in the karyotype; in addition, portions of the intergenic spacer (IGS) are clustered at chromosomal loci where they are not associated with ...
DE LUCCHINI, STEFANIA   +2 more
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