Results 221 to 230 of about 88,963 (266)
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Regulation of rDNA stability by sumoylation
DNA Repair, 2009Repair of DNA lesions by homologous recombination relies on the copying of genetic information from an intact homologous sequence. However, many eukaryotic genomes contain repetitive sequences such as the ribosomal gene locus (rDNA), which poses a risk for illegitimate recombination.
Eckert-Boulet, Nadine, Lisby, Michael
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The study of a rDNA replicator in Saccharomyces
Current Genetics, 1983We have previously demonstrated that the loss of Rcp-CEN3, a centromeric plasmid containing yeast rDNA autonomously replicating sequences (ARS) is as high as around 50% per generation for most yeast strains. In this study we have attempted to elucidate mechanisms underlying the high mitotic instability of Rcp-CEN3. For this purpose a tandem duplication
N Y, Kouprina, V L, Larionov
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Immunogenicity of rDNA-derived pharmaceuticals
Trends in Pharmacological Sciences, 2002Many biopharmaceuticals have been reported to induce the production of antibodies. Several factors influence immunogenicity, including the methods of production, formulation and storage as well as patient characteristics (e.g. type of disease and genetic background).
Ryff, J.C., Schellekens, H.
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rDNA and acrocentric chromosomes in man
Cell Differentiation, 1974A malformed female infant was found to have a 46,XX complement with a chromosome 8 shorter than normal with a secondary constriction and satellites on the short arm. Chromosome studies on the clinically normal father showed a balanced translocation between chromosome 8 and 13, i.e., 46,XY,t(8;13) (p21 p12). The proposita, carrier of the unbalanced form
G, Guanti, P, Petrinelli
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Chromosomal localization of rDNA in the gorilla
Cytogenetic and Genome Research, 1998Twenty-five specimens of lowland gorilla, including 24 specimens of the western lowland gorilla <i>(Gorilla gorilla gorilla) </i>and 1 specimen of the eastern lowland gorilla<i> (G. gorilla graueri), </i>were investigated by fluorescence in situ hybridization with a human-derived 18S + 28S rDNA probe.
W, Schempp, S, Zeitler, W, Rietschel
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rDNA transcription and cardiac hypertrophy
Trends in Cardiovascular Medicine, 1993A common result of the various stimuli that alter the growth rates of cells is a parallel alteration of the rate of ribosome biogenesis. In many cell types, this mandates an altered rate of ribosomal RNA synthesis. Preliminary studies indicate that rDNA transcription may in fact be regulated at more than one level or step.
W, Xie, L I, Rothblum
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Chromosomal localization of rDNA in the Brassicaceae
Genome, 2005A survey is given about the number and chromosomal position of rDNA loci in 45 Brassicaceae species. For 34 species, 5S and 45S rDNA loci have been localized by two-colour fluorescence in situ hybridization for the first time. These data show the variability of rDNA within karyotypes of the Brassicaceae, provide anchor points for (comparative) genetic
Hoda B M, Ali +2 more
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Biochemical and Biophysical Research Communications, 1993
In eukaryotes 5S rRNA genes are transcribed by RNA polymerase III. These genes occur in D. discoideum on the ca. 90 copies of an extrachromosomal palindrom together with the other ribosomal RNAs, which are generally transcribed by RNA polymerase I. A 5S rRNA gene has been isolated and its nucleotide sequence as well as the organization of the gene ...
J, Hofmann +6 more
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In eukaryotes 5S rRNA genes are transcribed by RNA polymerase III. These genes occur in D. discoideum on the ca. 90 copies of an extrachromosomal palindrom together with the other ribosomal RNAs, which are generally transcribed by RNA polymerase I. A 5S rRNA gene has been isolated and its nucleotide sequence as well as the organization of the gene ...
J, Hofmann +6 more
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Zoologica Scripta, 2006
We assess phylogenetic relationships within the polychaete family Hesionidae from morphological data combined with nucleotide data from 18S rDNA, 28S rDNA, 16S rDNA and COI. Parsimony and Bayesian analyses were performed on two data sets; the first was based on a more restricted set of terminals with both morphological and molecular data (17 ingroup ...
Christine Ruta +6 more
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We assess phylogenetic relationships within the polychaete family Hesionidae from morphological data combined with nucleotide data from 18S rDNA, 28S rDNA, 16S rDNA and COI. Parsimony and Bayesian analyses were performed on two data sets; the first was based on a more restricted set of terminals with both morphological and molecular data (17 ingroup ...
Christine Ruta +6 more
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