Results 151 to 160 of about 2,217,168 (245)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe₂. [PDF]

Nat Commun
Zambra V, Nathwani A, Nauman M, Lewin SK, Frank CE, Butch NP, Shekhter A, Ramshaw BJ, Modic KA.   +8 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Critical Isthmus Identification in Macro-Re-Entrant Atrial Tachycardia With Epicardial Conduction by Peak Frequency Mapping. [PDF]

JACC Case Rep
Kawafuji S, Yamaji H, Yamaoka R, Eda K, Shigyo K, Akiyama A, Kayama M, Sano M, Higashiya S, Kubo M, Murakami T, Kusachi S.   +11 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Intra-SVC re-entrant atrial tachycardia successfully treated with a circular multi-electrode array pulsed-field ablation catheter-case report. [PDF]

Eur Heart J Case Rep
Ikenaga T, Nozoe M, Mannoji H, Suematsu N, Kubota T.   +4 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

MANAGEMENT OF CHILDREN AFFECTED BY ATRIOVENTRICULAR NODAL RE-ENTRANT TACHICARDIA

, 2007
MANAGEMENT OF CHILDREN AFFECTED BY ATRIOVENTRICULAR NODAL RE-ENTRANT ...
NOVO, Giuseppina, PIPITONE, Sergio, MOSSUTO, Claudia, SUTERA L, GARAFFA G, NOVO, Salvatore, DE SANTIS, Antonio, FAZIO G, DRAGO F   +8 more
core  

Improving energy absorption capability of the hexagonal honeycomb and re-entrant structures using a combined hierarchical design. [PDF]

Sci Rep
Ashrafian MM, Hasanzadeh R.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source