Results 131 to 140 of about 2,217,168 (245)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Nodoventricular Orthodromic Re-Entrant Tachycardia Mimicking Slow/Fast Atrioventricular Nodal Re-Entrant Tachycardia: Electrophysiological Insights Into a Diagnostic Challenge. [PDF]

JACC Case Rep
Yamashita D, Kagawa Y, Tsumagari Y, Harada S, Shintani T, Uchida F, Dohi K.   +6 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Coupled re-entrant cavity system for electromagnetic levitation

, 2001
This paper describes a coupled re-entrant cavity system which is designed to provide an electric field distribution capable of generating levitation forces on a conducting plate located in the near-field of two or more non-radiating coupling apertures ...
Beale, G., McErlean, E., Kelly, M., Smith, P., Sangster, A. J.   +4 more
core  

A Novel Re-Entrant Honeycomb with Tunable Auxetic Response and Enhanced In-Plane Mechanical Performance. [PDF]

Materials (Basel)
Li C, Bai S, Yin J, Cao Q, Tian H, Dong Y, Wang H, Liu J, Que G, Chen Y.   +9 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Modeling Re-entrant Manufacturing Systems with Inspections

, 1995
Inspection stations are now an integral part of any manufacturing system and help track product quality and process performance. In this paper we consider re-entrant manufacturing systems (such as semiconductor fabrication facilities) with inspections at
Narahari, Y, Khan, LM
core  

Responses of re-entrant cylindrical tubes under internal loading

Re-entrant honeycomb core, which are a variation of the honeycomb in the shape of an hourglass, are part of the auxetic family which provides elevated energy absorption capabilities and structural strength.
Harold Tien Shi Chiang (19121113)
core   +1 more source

A Case of Atrioventricular Nodal Re-entrant Rhythm. [PDF]

J Innov Card Rhythm Manag
Mondal S, Muslim NA, Dhua D.
europepmc   +1 more source