Results 231 to 240 of about 53,167 (298)

The State of the Art in Combination Locoregional and Systemic Treatment Strategies for Hepatocellular Carcinoma: Recent Advancements and Future Horizons. [PDF]

Curr Oncol
Fazlollahi F, Carfora AD, King M, Wrasman ES, Makary MS.   +4 more
europepmc   +1 more source

Regioselective Synthesis of Benzylsilanols from Kobayashi‐Type Reagents via C(sp3)─H Bond Activating 1,4‐Palladium Migration

Angewandte Chemie, EarlyView.
A Pd‐catalyzed regioselective synthesis of benzylsilanols from Kobayashi‐type reagents has been developed through a mechanistically distinct approach involving 1,4‐Pd migration followed by intramolecular transmetalation. The reaction can be combined with various prior transition‐metal‐catalyzed processes and the resulting benzylsilanols have been ...
Ryo Shintani, Keisuke Tachibana
wiley   +1 more source

Serum pyruvate and lactate predict immunotherapy efficacy in advanced gastric cancer: a prospective biomarker study. [PDF]

Front Immunol
Liu C, Dai Y, Wang J, Wu J, Wei B.
europepmc   +1 more source

Spatial Detection of Microsphere Polystyrene Plastics and Molecular Remodeling within a Full‐Body Mouse with MALDI Trapped Ion Mobility Mass Spectrometry Imaging

Angewandte Chemie, EarlyView.
Orally administered polystyrene microplastics accumulate in murine tissues and are detected using MALDI‐MSI with TIMS. Lipid profiling reveals decreases in hexosylceramides, sphingomyelins, and ether‐linked phospholipids, indicating altered metabolism.
Karina A. Vargas, Amy L. Parkhurst, Ming‐Fo Hsu, Christopher Hou, Fawaz G. Haj, Elizabeth K. Neumann   +5 more
wiley   +1 more source

Axillary Surgery in Breast Cancer: Evidence-Based De-escalation Across Upfront and Post-Neoadjuvant Settings. [PDF]

J Breast Cancer
Park WK, Nam SJ, Kim SW, Yu J, Chae BJ, Lee SK, Ryu JM, Lee JE.   +7 more
europepmc   +1 more source

Room‐Temperature Gas‐Phase CO2‐to‐C3 Coupling by a 4f‐Aromatic Cluster

Angewandte Chemie, EarlyView.
We engineered a 4f metalla aromatic cluster, PrB2C2−, that enables efficient sequential C−C coupling with CO2 at room temperature, yielding a linear C3 backbone. This system provides a complete theoretical catalytic cycle and establishes a new design principle for lanthanide mediated CO2 activation.
Feng‐Xiang Zhang, Xiao‐Wang Li, Ning‐Zheng Li, Sheng‐Gui He, Yu‐Chen Zhang, Li‐Li Xing, Donald G. Truhlar, Jia‐Bi Ma   +7 more
wiley   +1 more source

The clarification of two hydroxylation steps in the conversion of cholesterol to OSW-1 in Ornithogalum saundersiae. [PDF]

Plant Biotechnol J
Zhang SY, Kong JQ.
europepmc   +1 more source

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

Angewandte Chemie, EarlyView.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner, Kai Rogge, Felix Trottmann, Christian Hertweck, Dirk Hoffmeister   +4 more
wiley   +1 more source

mzLearn as a data-driven LC/MS signal detection algorithm that enables pre-trained generative models for untargeted metabolomics. [PDF]

Commun Chem
Pirhaji L, Eaton J, Jeewajee AK, Zhang M, Morris M, Karasarides M.   +5 more
europepmc   +1 more source

One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade

Angewandte Chemie, EarlyView.
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra, Ruzal Sitdikov, Hasil Aman, Alyssio Calis, Gergely Laczkó, Virgile Rouffeteau, Maxime R. Vitale, Imre Pápai, Oscar Verho   +8 more
wiley   +1 more source