FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Carbonatites from the southern Brazilian Platform: A review. II: Isotopic evidences
Open Geosciences, 2020 Early and Late Cretaceous alkaline and alkaline–carbonatitic complexes from southern Brazil are located along the main tectonic lineaments of the South America Platform.
Speziale Sergio +5 more
doaj +1 more source
Identifying the origins of local atmospheric deposition in the steel industry basin of Luxembourg using the chemical and isotopic composition of the lichen Xanthoria parietina [PDF]
, 2008 Trace metal atmospheric contamination was assessed in one of the oldest European industrial sites of steel production situated in the southern part of the Grand-Duchy of Luxembourg.
Geagea, Majdi Lahd +6 more
core +3 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Re−Os Isotope and PGE Abundance Systematics of Coast Range Ophiolite Peridotites and Chromitite, California: Insights into Fore-Arc Magmatic Processes [PDF]
LithosphereWe report platinum-group element (PGE) and Re concentrations, and Re−Os isotopic data for peridotites and podiform chromitite from the mid-Jurassic Coast Range ophiolite (CRO), California.
Sung Hi Choi +3 more
doaj +1 more source
Carbon isotope anomaly in the major plant C-1 pool and its global biogeochemical implications [PDF]
, 2004 We report that the most abundant C-1 units of terrestrial plants, the methoxyl groups of pectin and lignin, have a unique carbon isotope signature exceptionally depleted in C-13.
Hamilton, JTG +4 more
core +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Yankuang ceshi, 2016 The east-central part of Jilin Province, located on the continental margin of northeast China along the eastern Xing-Meng orogenic belt, hosts more than 10 large-and medium-scale Mo deposits. The major types of mineralization include porphyry, skarn, and
SONG Quan-heng +5 more
doaj +1 more source
Exploring copepod distribution patterns at three nested spatial scales in a spring system. Habitat partitioning and potential for hydrological bioindication [PDF]
, 2015 In groundwater-fed springs, habitat characteristics are primarily determined by a complex combination of geomorphic features and physico-chemical parameters, while species assemblages are even more intricate.
Di Lorenzo, Tiziana +5 more
core +4 more sources
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source