Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Metre-scale vertical zonation of corals and sponges on a deep-marine cliff reflects trophic resource partitioning. [PDF]
Greenman W +8 more
europepmc +1 more source
Origin and Distribution of Large Asphaltite in South China. [PDF]
Zhu G +7 more
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The electronic spin state of two Chichibabin radicals is investigated using 2‐dimensional hyperfine correlated Electron Nuclear Double Resonance. The protons (I=1/2) act as a reference for the electronic spin quantum number (S) via their hyperfine interactions.
Gabriel Moise +7 more
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Cultural, economic, and settlement shifts over the last 9,000 years at Kakapel Rockshelter, Western Kenya. [PDF]
Goldstein ST +16 more
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Sustainable hydrogen production can be obtained from hydogen‐rich biomass‐derived organic molecules through Acceptorless Dehydrogenation (AD) reactions. Glycerol and sugars are available in large quantities from industry and can be successfully used as substrates in AD protocols, in the presence of tailored, selective, easily tunable and thermally ...
Sylwia Kostera, Luca Gonsalvi
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Multiproxy analysis unwraps origin and fabrication biographies of Sardinian figurines: On the trail of metal-driven interaction and mixing practices in the early first millennium BCE. [PDF]
Berger D +7 more
europepmc +1 more source
OMIP‐121: Immune Phenotyping of Canine Peripheral Leukocytes by Mass Cytometry
ABSTRACT Dogs are a critical non‐rodent species used in preclinical safety studies, particularly, in the pharmaceutical field, due to their physiological, metabolic, and immunological similarities to humans. As such, immunophenotyping of canine peripheral blood mononuclear cells (PBMCs) plays a crucial role in translational research, immune monitoring,
Huyen Thuc Tran Luong +5 more
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Human dietary diversity in the Colombian Andes at the terminal Pleistocene-late Holocene sites Tequendama and Aguazuque. [PDF]
Ziegler MJ +7 more
europepmc +1 more source
Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek +3 more
wiley +1 more source

