Results 71 to 80 of about 127,676 (332)
Advanced Healthcare Materials, EarlyView.This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik +2 more
wiley +1 more source
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
, 2016 BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc +12 more
core +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman +6 more
wiley +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
, 2018 Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Frontiers in Pharmacology, 2014 In the kidney, glucose in glomerular filtrate is reabsorbed primarily by sodium-glucose cotransporters 1 (SGLT1) and 2 (SGLT2) along the proximal tubules.
Yasong eLu +3 more
doaj +1 more source
, 2021 Dental reabsorptions can be classified as being caused by trauma, infection, or by a hyperplastic invasive, often idiopathic process. Objectives: The aim of this paper is to classify all types of dental reabsorptions based on their etiology. It will describe their pathogenesis, histologic manifestations, risk factors, and clinical or radiological ...
openaire +1 more source
Glucose Reabsorption in Experimental Glomerulonephritis
Experimental Biology and Medicine, 1977 SummaryThe relationship between glo-merular filtration rate and tubular glucose reabsorption was examined in rats with experimental glomerulonephritis. Glomerular filtration rates (single kidney) varied from 0.09 to 0.95 ml/min and superficial nephron filtration rates ranged from 4.4 to 38.2 nl/ min. A direct linear relationship between filtration rate
Juichi Kawamura +2 more
openaire +3 more sources
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source
SGLT2 Inhibitors and the Diabetic Kidney [PDF]
, 2016 Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca +4 more
core +1 more source
International Journal of Nephrology, 2012 The Na/K-ATPase is the primary force regulating renal sodium handling and plays a key role in both ion homeostasis and blood pressure regulation. Recently, cardiotonic steroids (CTS)-mediated Na/K-ATPase signaling has been shown to regulate fibrosis ...
Jiang Liu +3 more
doaj +1 more source