Results 241 to 250 of about 2,798,523 (312)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

UK dementia prevention policies and initiatives across the life-course: a scoping review (2009-2024). [PDF]

BMC Public Health
Luthra N, Islam AS.
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Intentional Intimal Tracking Via a 6-F Guiding Catheter Using a Novel Puncture Wire: The Solo Technique. [PDF]

JACC Case Rep
Liu H, Ma D, Huang Z, Han F, Chen Z, Sun X, Yang J, Xiong C, Jian L, Zhang B.   +9 more
europepmc   +1 more source

Better Dynamic Balance as a Predictor of Better Horizontal Hop Performance: A Cross-Sectional Study. [PDF]

Int J Sports Phys Ther
Pedersen MK, Kristensen SH, Hansen ER, Gade M, Kierkegaard-Brøchner S, Nielsen RØ, Jacobsen JS.   +6 more
europepmc   +1 more source

Cascade Dams and Seasonality Jointly Structure Gut Microbiome Biogeography in <i>Saurogobio punctatus</i>. [PDF]

Microorganisms
He R, Zhou K, Ni J, Chen Z, Yao C, Fu M, Lü H, Yao W.   +7 more
europepmc   +1 more source

Towards targeted drugs and next generation of nanomedicines. [PDF]

Beilstein J Nanotechnol
Salvati A, Giordani S, Parak WJ.
europepmc   +1 more source

Advancing global mental health through social media engagement: lessons from an international professional organization (IACAPAP). [PDF]

Child Adolesc Psychiatry Ment Health
Sravanti L, Hamoda HM.
europepmc   +1 more source

Effect of parent attendance at an adult commercial weight management programme on their children. [PDF]

BMJ Paediatr Open
Mears R, Sharp D, Searle A, Salway R, Hamilton-Shield J.   +4 more
europepmc   +1 more source