Results 51 to 60 of about 2,798,523 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Co-creation of community-based innovations to improve access to malaria treatment in conflict-affected regions of Cameroon

Malaria Journal
Background In conflict-affected regions of Cameroon, access to malaria care is severely hindered by displacement, insecurity, and disrupted health systems.
Lundi-Anne Omam, Elvis Asangbeng Tanue, Esther Njomo Omam, Alain Metuge, Isabelle Nganmou, Coril Epie, Gilbert Kebam, Solomon Ako, Margaret Ebob Bessem, Helen Hawkings, Kolawole Maxwell, Yakouba Zoungrana, Elizabeth Berryman, Elizabeth Jarman, Bibiche Modjenpa Noukeme   +14 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Zusammenfassung zu REACh

, 2022
6 FolienZusammenfassend werden die wichtigsten Auswirkungen von REACH und Stoffbeschränkungen in Produkten ...
Hornberger, Markus
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Wabanaki REACH Public Events, Fall 2021

, 2021
Event descriptions, dates, and times for Fall 2021 Wabanaki REACH programming.https://digitalcommons.library.umaine.edu/wabanaki_reach/1023/thumbnail ...
Wabanaki REACH
core   +1 more source

Different Evolutionary Origins for the Reach and the Grasp: An Explanation for Dual Visuomotor Channels in Primate Parietofrontal Cortex

Frontiers in Neurology, 2013
The Dual Visuomotor Channel Theory proposes that manual prehension consists of two temporally integrated movements, each subserved by distinct visuomotor pathways in occipitoparietofrontal cortex.
Jenni M Karl, Ian Q Whishaw
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Physical activity and physical activity promotion in Germany – An overview [PDF]

Journal of Health Monitoring
Background: Regular physical activity is essential for health, yet a large proportion of the German population remains inactive, with significant health and economic consequences.
Sven Messing, Leonie Birkholz, Julian Resch, Johannes Brandl, Eva Lorenz, Karim Abu-Omar, Wolfgang Geidl, Antonina Tcymbal, Peter Gelius, Klaus Pfeifer   +9 more
doaj   +1 more source