Results 241 to 250 of about 1,777,295 (308)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

External Validation of the REACT-HF Score for Predicting Heart Failure in Patients With Atrial Fibrillation. [PDF]

J Am Heart Assoc
Moschovitis G, Rigamonti E, Wiencierz A, Coslovsky M, Blum S, De Perna ML, Mayer-Melchiorre P, Vassalli G, Pedrazzini G, Healey JS, Reichlin T, Rodondi N, Müller A, Beer JH, Conte G, Stuber M, Schwenkglenks M, Mahfoud F, Sticherling C, Conen D, Osswald S, Kühne M, Krisai P, Swiss‐AF and BEAT‐AF Investigators.   +23 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Difficult Conversation Case: Missed Testicular Cancer. [PDF]

J Educ Teach Emerg Med
Ginsburg J, Zamamiri S, Howell M, Parnell S, Milman B.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Pyridine-boryl radical mediated synthesis of quinolines <i>via</i> α-amino radical formation and intramolecular alkenyl sulfone trapping.

Org Chem Front
Valderrama-Callejón R, Alonso I, Gómez S, Jiménez D, Dorado-Briones G, Vargas EL, Tortosa M, Cid MB.   +7 more
europepmc   +1 more source

OLIVE provides rapid visualization and analysis of chromatin tracing experiments. [PDF]

Cell Rep Methods
Zhou Y, Sheng Y, Hu D, Jay A, Vahedi G, Faryabi RB.   +5 more
europepmc   +1 more source

Pattern matching with Elastic-Degenerate strings and Elastic-Founder graphs. [PDF]

Algorithms Mol Biol
Ascone R, Bernardini G, Conte A, Equi M, Gabory E, Grossi R, Pisanti N.   +6 more
europepmc   +1 more source

Hyperdense Aneurysm Visualized at the Occlusion Site During Thrombectomy: A Case Report. [PDF]

Cureus
Kaneko R, Ikeda H, Fujiwara T, Yoshida S, Uezato M, Kinosada M, Kurosaki Y, Chin M.   +7 more
europepmc   +1 more source