Results 71 to 80 of about 435,439 (266)

React-tRace: A Semantics for Understanding React Hooks: An Operational Semantics and a Visualizer for Clarifying React Hooks

open access: yesProceedings of the ACM on Programming Languages
React has become the most widely used web front-end framework, enabling the creation of user interfaces in a declarative and compositional manner. Hooks are a set of APIs that manage side effects in function components in React. However, their semantics are often seen as opaque to developers, leading to UI bugs.
Jay Lee, Joongwon Ahn, Kwangkeun Yi
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Semantics for the Essence of React.

open access: yes, 2020
Traditionally, web applications have been written as HTML pages with embedded JavaScript code that implements dynamic and interactive features by manipulating the Document Object Model (DOM) through a low-level browser API. However, this unprincipled approach leads to code that is brittle, difficult to understand, non-modular, and does not facilitate ...
Magnus Madsen, Ondrej Lhoták, Frank Tip
openaire   +3 more sources

Reacting into new frameworks [PDF]

open access: yesScience, 2016
Materials Chemistry Covalent organic frameworks (COFs) are formed through moderately strong bonds between multidentate centers and organic linkers. One difficulty in using very strong linkages to create more robust materials is that the process of crystallization must allow for error correction, so the linkages must be weak enough to be reversible ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Efficient solar-driven degradation of diclofenac in aquatic environments using Cu-TiO2/Kaolin thin films: insights from different water matrices

open access: yesDiscover Chemical Engineering
Photocatalysis has gained considerable attention for the degradation of hazardous pollutants. In this study, the photocatalytic efficiency of Cu(0.50%)/TiO₂/Kaolin thin films was evaluated for the removal of diclofenac (DCF), a widely used non-steroidal ...
Saad Slimani Tlemcani   +5 more
doaj   +1 more source

REACT

open access: yes, 2016
n ...
Milo, Tova, Somech, Amit
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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