Results 41 to 50 of about 111,699 (262)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Solving the Caputo Fractional Reaction-Diffusion Equation on GPU
Discrete Dynamics in Nature and Society, 2014 We present a parallel GPU solution of the Caputo fractional reaction-diffusion equation in one spatial dimension with explicit finite difference approximation.
Jie Liu +4 more
doaj +1 more source
Trotter products and reaction–diffusion equations
Journal of Computational and Applied Mathematics, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Maximum Principles for Discrete and Semidiscrete Reaction-Diffusion Equation
Discrete Dynamics in Nature and Society, 2015 We study reaction-diffusion equations with a general reaction function f on one-dimensional lattices with continuous or discrete time ux′ (or Δtux)=k(ux-1-2ux+ux+1)+f(ux), x∈Z.
Petr Stehlík, Jonáš Volek
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Results in Physics, 2019 Effect of chemical reaction on Li-ions diffusion and diffusion-reaction-induced stresses in a spherical electrode is studied, considering the reaction rate determined by the relation between hydrostatic stress and activation enthalpy, to derive new ...
Liangxinbu Lyu +4 more
doaj +1 more source
Convolution Representation of Traveling Pulses in Reaction-Diffusion Systems
Advances in Mathematical Physics, 2023 Convolution representation manifests itself as an important tool in the reduction of partial differential equations. In this study, we consider the convolution representation of traveling pulses in reaction-diffusion systems.
Satoshi Kawaguchi
doaj +1 more source