Results 111 to 120 of about 9,642,220 (333)

¿Mutismo selectivo infantil en tiempos de COVID-19? A propósito de un caso. Selective infant mutism in times of COVID-19? About a case.

open access: yesRevista GICOS, 2020
Se trata de un caso de preescolar femenina de 6 años de edad, procedente de la ciudad de Mérida, Venezuela, quien presenta mutismo selectivo, como síntoma asociado a su reacción adaptativa emocional dada por la migración de padre y se exacerba en los ...
Rosa Márquez
doaj  

Out-of-plane pion emission in relativistic heavy ion collisions: Spectroscopy of Delta resonance matter [PDF]

open access: yes, 2006
Azimuthal correlations of pions are studied with the quantum molecular dynamics model. Pions are preferentially emitted perpendicular to the reaction plane.
Bass, Steffen A.   +3 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Reaction curves [PDF]

open access: yes
A reaction curve RC, also called reaction function or best-reply function, is the locus of optimal, i.e. profit-maximizing, actions that a firm may undertake for any given action chosen by a rival firm.
Giocoli, Nicola
core   +1 more source

Recursive POD expansion for the advection-diffusion-reaction equation [PDF]

open access: yes, 2018
This paper deals with the approximation of advection-diffusion-reaction equation solution by reduced order methods. We use the Recursive POD approximation for multivariate functions introduced in [M. AZAÏEZ, F. BEN BELGACEM, T. CHACÓN REBOLLO, Recursive
Azaïez, Majdi   +3 more
core  

On a Conjecture of Goriely for the Speed of Fronts of the Reaction--Diffusion Equation

open access: yes, 1996
In a recent paper Goriely considers the one--dimensional scalar reaction--diffusion equation $u_t = u_{xx} + f(u)$ with a polynomial reaction term $f(u)$ and conjectures the existence of a relation between a global resonance of the hamiltonian system ...
A. Goriely   +12 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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