Results 41 to 50 of about 35,427 (268)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effects of Internal Pressure and Inlet Velocity Disturbances of Air and Fuel Droplets on Spray Combustion Field

Journal of Thermal Science and Technology, 2013
Effects of internal pressure and inlet velocity disturbances of air and fuel droplets on spray combustion field are investigated by means of two-dimensional direct numerical simulation (DNS).
Tomoaki KITANO, Ryoichi KUROSE, Satoru KOMORI   +2 more
doaj   +1 more source

Irreversibility analysis in Darcy-Forchheimer flow of viscous fluid with Dufour and Soret effects via finite difference method

Case Studies in Thermal Engineering, 2021
Background and objective: Here irreversibility analysis in unsteady Darcy-Forchheimer flow of viscous fluid by a stretched sheet is examined. Lorentz force effect is considered.
Sohail A. Khan, T. Hayat, A. Alsaedi
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Computational framework for thermal transportation in radiative bio-convective micropolar nanomaterial flow over stretched sheet with entropy optimization

Case Studies in Thermal Engineering
Entropy generation (EG) in bioconvective nanofluid flows is a phenomenon that occurs due to the presence of nanoparticles and microorganisms within fluid flows. EG leads to an increase in thermodynamic irreversibility within the system. Understanding and
Si Jun Tao, Fazal Haq, Arshad Hussain, Ali Shokri, Mohamed R. Ali, Ahmed S. Hendy   +5 more
doaj   +1 more source

Comparison between the flow of two non-Newtonian fluids over an upper horizontal surface of paraboloid of revolution: Boundary layer analysis

Alexandria Engineering Journal, 2016
Boundary layer flow of two non-Newtonian fluids past an upper horizontal surface of a paraboloid of revolution (uhspr) in the presence of nonlinear thermal radiation is investigated.
O.A. Abegunrin, S.O. Okhuevbie, I.L. Animasaun   +2 more
doaj   +1 more source

A thermodynamical model for population growth with relaxation phenomena

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2022
Reaction-diffusion models were used in dynamic fluid, population growth, pulse propagation in nerves and other biological phenomena. Some of these models have been expanded to describe memory effects in diffusion and therefore with the use of hyperbolic ...
Vincenzo Ciancio, Antonella Lupica, Annunziata Palumbo   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source