Results 51 to 60 of about 35,427 (268)

Unsteady magneto reactive heat transfer in Casson dusty fluid under Couette Poiseuille flow with variable chemical kinetics

open access: yesAlexandria Engineering Journal
This study analyzes the unsteady magnetohydrodynamic (MHD) flow and heat transfer of a chemically reactive Casson dusty fluid under variable two-step exothermic reaction kinetics in a Couette–Poiseuille configuration.
Dolat khan   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Continuous Synthesis of Monodispersed Alumina Particles by the Hydrolysis of Metal Alkoxide Using a Taylor Vortex [Translated]†

open access: yesKONA Powder and Particle Journal, 2014
A continuous reactor was developed for industrial production of monodispersed alumina particles from metal alkoxide. Taylor vortex flows were used for solution mixing.
Takashi Ogihara, Mamoru Nomura
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Viscoelastic rotational free convection and coupled heat-mass transfer flow with heat generation and chemical reaction effects

open access: yesDiscover Mechanical Engineering
This work examines the free convection rotational flow of a second-grade (viscoelastic) fluid when a first-order chemical reaction and heat production are present.
Rashid Ayub   +7 more
doaj   +1 more source

Thermo-magnetic stratified flow capturing Soret-Dufour impacts in rate type reactive material under varying liquid aspects and stratifications

open access: yesInternational Journal of Thermofluids
In various industrial frameworks encompassing biofluids, polymers and coatings, interpreting viscoelastic characteristics is indispensable for accomplishing regulated mass and heat transmission.
F. Shahzad   +7 more
doaj   +1 more source

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