Results 51 to 60 of about 37,264 (315)

Comparison between the flow of two non-Newtonian fluids over an upper horizontal surface of paraboloid of revolution: Boundary layer analysis

Alexandria Engineering Journal, 2016
Boundary layer flow of two non-Newtonian fluids past an upper horizontal surface of a paraboloid of revolution (uhspr) in the presence of nonlinear thermal radiation is investigated.
O.A. Abegunrin, S.O. Okhuevbie, I.L. Animasaun   +2 more
doaj   +1 more source

Reaction Systems for Bubbly Flows

, 2018
Reactive bubbly flows are at the heart of multiphase flows which are a major topic in chemical engineering since many bulk chemicals are produced in bubbly flows.
Sonja Herres‐Pawlis, Strassl, Florian, Hoffmann, Marko, Marko Hoffmann, Paul, Melanie, Hoffmann, Alexander, Michael Schlüter, Herres-Pawlis, Sonja, Schlüter, Michael, Florian Strassl, Alexander Hoffmann, Melanie Paul   +11 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Unsteady magneto reactive heat transfer in Casson dusty fluid under Couette Poiseuille flow with variable chemical kinetics

Alexandria Engineering Journal
This study analyzes the unsteady magnetohydrodynamic (MHD) flow and heat transfer of a chemically reactive Casson dusty fluid under variable two-step exothermic reaction kinetics in a Couette–Poiseuille configuration.
Dolat khan, Gohar Ali, Zeeshan Ali, Zailan Siri, Burhan Ud Din   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Continuous Synthesis of Monodispersed Alumina Particles by the Hydrolysis of Metal Alkoxide Using a Taylor Vortex [Translated]†

KONA Powder and Particle Journal, 2014
A continuous reactor was developed for industrial production of monodispersed alumina particles from metal alkoxide. Taylor vortex flows were used for solution mixing.
Takashi Ogihara, Mamoru Nomura
doaj   +1 more source

Modelling of turbulent swirling flows [PDF]

, 2004
This thesis investigates the predictability of non-reacting and reacting anistropic turbulent, swirling flows using popular turbulence models with a robust numrical procedure. The performance of these turbulence models is assessed and compared against
Jones, Lee Nicholas
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source