Results 111 to 120 of about 1,729,497 (317)

Impedance spectroscopy: A useful technique to unveil the mechanism of a CO oxidation reaction [PDF]

open access: yes
In this work, the impedance spectroscopy (IS) technique was used to aid in understanding the reaction mechanism of the CO oxidation reaction using the Pr2Zr2-xFexO7±d (x = 0 and 0.10) mixed oxide as a heterogeneous catalyst.
Dos Santos Veiga, Emerson Luiz   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Effects of the Y432S Cancer-Associated Variant on the Reaction Mechanism of Human DNA Polymerase κ

open access: yes
Human polymerases are vital for genetic information management. Their function involves catalyzing the synthesis of DNA strands with unparalleled accuracy, which ensures the fidelity and stability of the human genomic blueprint.
Emmett M., Leddin   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Teaching and learning strategies of organic reaction mechanism in pre-university chemistry: a scoping review [PDF]

open access: yes
Teaching Organic Chemistry has always been viewed as difficult to teach, where learners are frequently repelled by the topic’s high level of complexity, which appears to discriminate against the subject.
Muhamad, M.M.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

DFT investigation on the reaction mechanism catalyzed by α-phosphomannomutase1 in protonated deprotonated states

open access: yes, 2011
DFT investigation on the reaction mechanism catalyzed by α-phosphomannomutase1 in protonated/deprotonated ...
楚慧郢   +6 more
core  

Reaction mechanism for methanol oxidation on Au(1 1 1): A density functional theory study

open access: yes, 2013
The microscopic reaction mechanism for methanol oxidation on Au(1 1 1) surface has been thoroughly investigated by means of density functional theory (DFT) computations.
Liu, Shuping   +5 more
core   +1 more source

Reaction mechanism.

open access: yes, 2020
Reaction mechanism of the reaction of 1 with L-cysteine methyl ester via a cationic azomethine A to form the thiazolidine 16.
Peter M. Piermarini (8496270)   +6 more
core   +1 more source

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