Recent Advances in Catalytic Conversion of Bioethanol to 1,3-Butadiene: Reaction Mechanism, Catalyst Design, and Process Scalability. [PDF]
Varma AR +7 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
An S<sub>N</sub>2 reaction mechanism for hydrolysis of siloxane linkages and the implications for dissolution of quartz. [PDF]
Watts HD, Kubicki JD.
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Unveiling the reaction mechanism and the regioselectivity of Diels-Alder cycloadditions between 2-methoxy-3-thiophenylbutadiene and methyl vinyl ketone using topological tools. [PDF]
Chellegui M +4 more
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Study on Decarburization Behavior in BOF Steelmaking Based on Multi-Zone Reaction Mechanism. [PDF]
Xin Z, Lin W, Zhang J, Liu Q.
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Electrochemical Surface Composition of Iridium Oxide IrO<sub>2</sub>(110): Implications for the Oxygen Evolution Reaction Mechanism. [PDF]
Arevalo RL, Gueriba JS, Nakanishi H.
europepmc +1 more source

