Results 231 to 240 of about 3,330,189 (298)

Tracking the correlation between spintronic structure and oxygen evolution reaction mechanism of cobalt-ruthenium-based electrocatalyst. [PDF]

Nat Commun
Wang C, Deng C, Zhai P, Shi X, Liu W, Jin D, Shang B, Gao J, Sun L, Hou J.   +9 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Exploring the Reaction Mechanism of Polyethylene Terephthalate Biodegradation through QM/MM Approach. [PDF]

J Phys Chem B
Dos Santos AM, da Costa CHS, Silva PHA, Skaf MS, Lameira J.   +4 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Complete Computational Reaction Mechanism for Foldamer-Catalyzed Aldol Condensation. [PDF]

ACS Catal
Brown RO, Demapan D, Cui Q.
europepmc   +1 more source

Rhodium-Catalyzed Arene Alkenylation: Selectivity and Reaction Mechanism as a Function of In Situ Oxidant Identity. [PDF]

Organometallics
Bennett MT, Park KA, Gunnoe TB.
europepmc   +1 more source

Molecular basis of the reaction mechanism of the methyltransferase HENMT1. [PDF]

PLoS One
Kaldis P, Zhao LN.
europepmc   +1 more source

Preparation of Consolidated Dust Suppression Materials Based on Pectin: Graft Modification Experiment and Reaction Mechanism. [PDF]

ACS Omega
Shi S, Wang XH, Jiang B, Tao W, Yu CF, Ji B.   +5 more
europepmc   +1 more source

Insights into glucose-derived carbon dot synthesis via Maillard reaction: from reaction mechanism to biomedical applications. [PDF]

Sci Rep
Cho S, Kim H, Song D, Jung J, Park S, Jo H, Seo S, Han C, Park S, Kwon W, Han H.   +10 more
europepmc   +1 more source

QM/MM Study of the Reaction Mechanism of L-Tyrosine Hydroxylation Catalyzed by the Enzyme CYP76AD1. [PDF]

J Phys Chem B
Sousa JPM, Ramos MJ, Fernandes PA.
europepmc   +1 more source