Results 131 to 140 of about 14,626,809 (402)

A paramedic treatment for modeling explicitly solvated chemical reaction mechanisms

Chemical Science, 2018
A static QM procedure for modeling solvated reaction mechanisms is calibrated using the Morita–Baylis–Hillman reaction.
Yasemin Basdogan, J. Keith
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Application of Mass Spectrometry in New Energy Fields

Zhipu Xuebao
The development and utilization of environment-friendly energy is imminent with global energy shortage and climate change becoming increasingly serious.
Shi-han LI, Chao QIAN, Shao-dong ZHOU
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A comparison of reaction diffusion and mechanochemical models for limb development [PDF]

, 1991
Several theoretical models have been proposed to attempt to elucidate the underlying mechanisms involved in the spatial patterning of skeletal elements in the limb.
Maini, P. K.
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Advances in the development and characterization of combustible cartridge cases and propellants: Preparation, performance, and future prospects

Reviews on Advanced Materials Science
This study presents a comprehensive analysis of combustible cartridge cases (CCCs) and propellants with a focus on their preparation methods, characterization techniques, and application in modern weaponry.
Wu Mengde, Xiao Zhenggang
doaj   +1 more source

Exploring the mechanisms of large local reactions to insect bites in patients with chronic lymphocytic leukaemia [PDF]

, 2016
Jamma Li, Giles Best, Stephen P. Mulligan, Suran L. Fernando   +3 more
openalex   +1 more source

Finite Rate Reaction Mechanism Adapted for Modelling Pseudo-Equilibrium Pyrolysis of Cellulose [PDF]

, 2022
Tomás Mora Chandía
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source