Results 151 to 160 of about 14,001,607 (382)
A STUDY OF THE MECHANISM OF THE GRIGNARD REACTION. [PDF]
Lambert. Thorp, Oliver Kamm
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TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
THE CHEMICAL MECHANISM OF BACTERIAL BEHAVIOR II. A NEW THEORY OF THE GRAM REACTION [PDF]
Esther Wagner Stearn, Allen E. Stearn
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Principal basis for enzyme power [PDF]
The reaction rate enhancement that enzymes produce had not been fully appreciated. The object of the article is to present the mechanism of the enormous catalytic power of the enzymes.
Alexander G. Foigel
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Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
THE RESPONSE OF THE RESPIRATORY MECHANISM TO RAPID CHANGES IN THE REACTION OF THE BLOOD [PDF]
John P. Peters
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Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Effect of silica fume additions on the hydration behaviour of calcium aluminates [PDF]
In the recent refractory castables technology, the calcium aluminate cement is being replaced in increasing proportion by very fine matrix components, such as silica fume and colloidal alumina.
Fumo, Daniel A., Segadães, Ana M.
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source