Results 151 to 160 of about 5,905,665 (347)

Effect of Body Mass Index on Audiovisual Reaction Time in Healthy Young Males

open access: hybrid, 2017
Brajpal Singh Tanwar   +3 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Comparing Performance of Volleyball Players and Non Sport Practing People on Volluntary and Automatic Orienting Visual Attention Tasks: An Exploratory Study

open access: yesPsicologia, 2009
Attention is the selection of information to improve central nervous system functioning. In this study, reaction times (RT) of 6 volleyball players and 6 non sports practitioners were compared during voluntary and automatic orienting of attention tasks ...
Luiz Renato Rodrigues Carreiro   +2 more
doaj  

Influence of reaction time on the structure of polyaniline synthesized on a pre-pilot scale [PDF]

open access: hybrid, 2018
Maria Alice Carvalho Mazzeu   +4 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Detection of bacteria in platelet concentrates: comparison of broad‐range real‐time 16S rDNA polymerase chain reaction and automated culturing

open access: green, 2005
Tamimount Mohammadi   +4 more
openalex   +2 more sources

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