Results 41 to 50 of about 1,323,182 (282)

Shigella flexneri associated reactive arthritis - GI transmitted or sexually transmitted?

Journal of Family Medicine and Primary Care, 2019
The pathogenic association of reactive arthritis with human immunodeficiency virus (HIV) needs more attention. In this case report we described a case of 22 year old male patient suffering from severe HIV infection.
Nidhi Kaeley, Manish Kumar, Bharat B Bhardwaj, Vempalli Nagasubramanyam   +3 more
doaj   +1 more source

Self-reactive T cells induce and perpetuate chronic relapsing arthritis

, 2020
Background: CD4+ T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is still not fully understood.
Wester-Rosenlöf, Lena, Hopkins, Malin Hultqvist,, Haag, Sabrina, Olofsson, Peter,, Carlsen, Stefan, Holmberg, Jens,, Wester-Rosenlöf, Lena,, Olofsson, Peter, Hopkins, Malin Hultqvist, Tuncel, Jonatan, Carlsen, Stefan,, Holmberg, Jens, Haag, Sabrina,, Holmdahl, Rikard, Tuncel, Jonatan,, Lund University., Holmdahl, Rikard,, Olofsson, P, Tuncel, J, Haag, S, Wester-Rosenlof, L, Holmdahl, R,, Hopkins, MH, Holmberg, J, Carlsen, S, Rikard Holmdahl, Jens Holmberg, Sabrina Haag, Stefan Carlsen, Peter Olofsson, Jonatan Tuncel, Lena Wester-Rosenlöf, Malin Hultqvist Hopkins   +32 more
core   +1 more source

Reactive Arthritis Following Intravesical Instillation of Bacillus Calmette-Guerin

The Turkish Journal of Gastroenterology, 2014
Reactive arthritis is a seronegative, HLA-B27-linked spondyloarthropathy which occurs as a result of a pathogen, often of gastrointestinal or genitourinary origin, and triggers a cell-mediated immune response.
Selin HASSAN, Peyman YALÇIN, Şebnem ATAMAN, Nurben SÜLDÜR   +3 more
doaj   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1 beta-mediated cartilage degradation [PDF]

, 2010
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Martin M Knight, Mistry, Jiten, Michael-Titus, Adina T., Blain, Emma Jane, Michael-Titus, AT, Wann, Angus K. T., Angus KT Wann, Wann, Angus K.T., Emma J Blain, Knight, MM, Knight, Martin M., Blain, EJ, Adina T Michael-Titus, Blain, Emma J., Wann, AKT, Mistry, J, Jiten Mistry   +16 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Reactive arthritis in tuberculosis: A case of Poncet’s disease [PDF]

, 2013
Reactive arthritis and erythema are uncommon presentations of tuberculosis (TB). Reactive arthritis in tuberculosis (TB) is known as Poncet’s disease, a rare aseptic form of arthritis observed in patients with active TB.
Hassan, Faezah, Faezah H, Irmi ZI, Ismail, Irmi Zarina, Ahmad, Zaiton, Zaiton A   +5 more
core   +2 more sources

Role of reactive oxygen and nitrogen species in formation of acute and chronic experimental arthritis

Біологічні студії, 2014
Free radical oxidation processes is an important link of rheumatoid arthritis pathogenesis. Reactive oxygen species and reactive nitrogen species are formed during cellular oxidative phosphorylation.
I. I. Kril, A. M. Gavrylyuk, A. V. Kotsyuruba, Y. Y. Kit, V. V. Chopyak, R. S. Stoika   +5 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source