Results 41 to 50 of about 1,084,746 (276)

Reactive arthritis – an interdisciplinary issue

Przegląd Dermatologiczny, 2019
Reactive arthritis is an aseptic inflammation of synovium, tendons and fasciae triggered by an immunological reaction to a distant-site infection. It is usually asymmetric.
Ewelina Biało-Wójcicka, Karolina Rutkowska, Kalina Wysocka-Dubielecka   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Shigella flexneri associated reactive arthritis - GI transmitted or sexually transmitted?

Journal of Family Medicine and Primary Care, 2019
The pathogenic association of reactive arthritis with human immunodeficiency virus (HIV) needs more attention. In this case report we described a case of 22 year old male patient suffering from severe HIV infection.
Nidhi Kaeley, Manish Kumar, Bharat B Bhardwaj, Vempalli Nagasubramanyam   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Self-reactive T cells induce and perpetuate chronic relapsing arthritis

, 2020
Background: CD4+ T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is still not fully understood.
Wester-Rosenlöf, Lena, Hopkins, Malin Hultqvist,, Haag, Sabrina, Olofsson, Peter,, Carlsen, Stefan, Holmberg, Jens,, Wester-Rosenlöf, Lena,, Olofsson, Peter, Hopkins, Malin Hultqvist, Tuncel, Jonatan, Carlsen, Stefan,, Holmberg, Jens, Haag, Sabrina,, Holmdahl, Rikard, Tuncel, Jonatan,, Lund University., Holmdahl, Rikard,   +16 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Characteristics of the Onset and Evolution of Juvenile Rheumatoid Arthritis Symptoms during the First Year of its Development

Zdorovʹe Rebenka, 2015
The article presents the data about early symptoms of juvenile rheumatoid arthritis in comparison with the reactive arthritis. Description of the articular syndrome is provided, the incidence of isolated joints affection and radiologic abnormalities in ...
I.S. Lebets, N.O. Panko, O.V. Matviienko, Ye.M. Zaitseva, N.S. Shevchenko   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

24-hour activity and sleep profiles in arthritis

, 2020
Objectives: Identify 24-hour activity-sleep profiles in adults with arthritis and explore factors associated with profile membership. Methods: Cross-sectional cohort, using baseline data from two randomized trials studying activity counselling for ...
Feehan, Lynne M., Lynne M. Feehan, Na Lu, Lu, Na, Xie, Hue, Li, Linda C., Linda C. Li, Hui Xie   +7 more
core   +1 more source

Diagnosis and treatment of reactive arthritis

Медицинский совет, 2014
The article discusses clinical manifestations of reactive arthritis, problems of diagnosis and treatment. The role of rational antibiotic therapy in the treatment of various forms of reactive arthritis is emphasized.
V. V. Badokin
doaj   +1 more source