Results 81 to 90 of about 1,084,746 (276)

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

American College of Rheumatology/European League Against Rheumatism Provisional Definition of Remission in Rheumatoid Arthritis for Clinical Trials [PDF]

, 2011
Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there is no widely used definition of remission that is stringent but achievable and could be applied uniformly as an outcome measure in clinical trials.
Matucci-Cerinic, M., Richards, P., American College of Rheumatology,, Robert Landewé, Pamela Richards, Alan Tyndall, Wit, M. de, Siegel, Jeffrey N., John Kirwan, Gillian Hawker, Daniel Aletaha, Simon, L.S., Dougados, Maxime, White, Barbara, Montie, Pamela, Kvien, T.K., Andrew Brown, Funovits, J., Combe, Bernard, Aletaha, Daniel, Tuyl, H.D. van, Tuulikki Sokka, Brooks, Peter, Brown, Andrew, Kirwan, J, Josef S. Smolen, Bathon, J., Suzan Verstappen, Choi, Hyon, Allaart, Cornelia F, Furst, Daniel E., Kaleb Michaud, Heijde, D. van der, van der Heijde, D., George Wells, Cornelia F Allaart, Furst, D., Landewe, R., Josef S Smolen, Brooks, Peter M., Allaart, Cornelia F., Sokka, Tuulikki, Maarten de Wit, David T. Felson, Peter Brooks, Verstappen, Suzan, Boers, M., Choi, H., Khanna, Dinesh, Khanna, D., Aletaha, D., Strand, Vibeke, Bombardieri, Stefano, Kvien, Tore K., Wolfe, F, Boers, Maarten, Stefano Bombardieri, Listing, J., Tugwell, P, Zhang, B., Joan Bathon, Lee S. Simon, Barbara White, Richards, Pamela, Wolfe, Frederick, Sokka, T., Maxime Dougados, Angela Zink, van Tuyl, Lilian H. D., van Tuyl, H.D., Hawker, G., Brown, A., Felson, David T., Paul Emery, Keystone, E., Bathon, Joan, Listing, Joachim, Verstappen, S., Zink, Angela, Combe, B., Michaud, K., Hyon Choi, Wolfe, F., Daniel Furst, Joachim Listing, Funovits, Julia, Gomez-Reino, J., de Wit, Maarten P. T., Emery, Paul, Gomez-Reino, Juan, Wells, George, Jeffrey N Siegel, Lilian H D van Tuyl, Theodore Pincus, Zink, A., Michaud, Kaleb, Marco Matucci-Cerinic, Tyndall, A., Lee S Simon, Keystone, Edward, European League Against Rheumatism,, Landewé, Robert, Emery, P., Julia Funovits, Zhang, Bi, Jeffrey N. Siegel, Maarten Boers, Van Tuyl, Lilian H D, de Wit, Maarten, Pincus, T., Hawker, Gillian, Strand, V., Edward Keystone, Frederick Wolfe, Martin-Mola, E., Pamela Montie, de Wit, M., van Tuyl, L.H.D., Tore K. Kvien, Cornelia F. Allaart, Emilio Martin-Mola, Matucci-Cerinic, Marco, Emery, P, Zhang, Bin, Tyndall, Alan, Bernard Combe, Dougados, M., Kirwan, J., David T Felson, Tugwell, Peter, Allaart, C.F., Brown, A, Juan Gomez-Reino, Vibeke Strand, Tuyl, L.H.D. van, Montie, P., Brooks, P., Peter Tugwell, Kirwan, John, Simon, Lee S., Furst, Daniel, Bombardieri, S., van der Heijde, Desirée, Dinesh Khanna, White, B., Pincus, Theodore, Wells, G., Siegel, J.N., Martin-Mola, Emilio, Tugwell, P., Felson, D.T., Desirée van der Heijde, Smolen, Josef S., Lilian H. D. van Tuyl, Smolen, J.S., Strand, V, Bin Zhang   +156 more
core   +2 more sources

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

Frailty Predicts Incident Osteoporotic Fractures in Veterans with Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Rheumatoid arthritis (RA) is associated with an increased risk of frailty and osteoporosis, but the relationship between frailty and incident osteoporotic fractures in RA is underexplored. Methods Data were from the Veterans Affairs (VA) Rheumatoid Arthritis Registry. Frailty was measured using the VA Frailty Index (VAFI).
Katherine D. Wysham, Hannah F. Brubeck, Aaron Baraff, Punyasha Roul, Namrata Singh, James S. Andrews, Grant W. Cannon, Gary A. Kunkel, Ted R. Mikuls, Bryant R. England, Dolores M. Shoback, Patricia P. Katz, Jose M. Garcia, Ariela R. Orkaby, Joshua F. Baker   +14 more
wiley   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Counting the cost: the current and future burden of arthritis

, 2016
A major new report shows the growing multi-billion dollar costs of arthritis to the economy, individuals and to the healthcare system and how relatively small investments could yield savings of more than $170 million a year.
Arthritis Australia
core  

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Increased chitotriosidase activities in patients with rheumatoid arthritis: A possible novel marker? [PDF]

Journal of Medical Biochemistry, 2014
Background: Chitotriosidase and YKL-40 are well-known in humans as Glyco_18 domain-containing proteins that are the common feature of mammalian chitinases and chitinase-like proteins.
Basok Banu Isbilen, Kucur Mine, Kizilgul Muhammed, Yilmaz Ibrahim, Ekmekci Ozlem Balci, Uzunlulu Mehmet, Isman Ferruh Kemal   +6 more
doaj  

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source