REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
Kinetic analysis and comparison of the coking behavior of coal Tar oil. [PDF]
Miroshnichenko D +4 more
europepmc +1 more source
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen +11 more
wiley +1 more source
Numerical investigation of vanadium distill-condensation <i>via</i> computational fluid dynamics. [PDF]
Yang Z +5 more
europepmc +1 more source
Continuous wet‐spinning of PANI with TeNWs yields a multifunctional microfiber. Oriented TeNWs impose chain alignment and enhance π‐electron delocalization, boosting the Seebeck coefficient to 59.9 µV K−1 for passive temperature sensing (1 K detection limit), while achieving high pH sensitivity (59.25 mV pH−1) and rapid NH3 response (0.96 s).
Dongmei Xie +10 more
wiley +1 more source
Process Modeling and Techno-economic Analysis of an Integrated Large-Scale CO<sub>2</sub>/CO Electroreduction Plant to Produce C<sub>2+</sub> Products. [PDF]
Sajeev A +5 more
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3D printing enables a high entropy alloy‐derived, in situ formed MnOx overlayer that suppresses oxidation–reconstruction and mitigates anodic dissolution, while enhancing electrolyte wetting and bubble release to accelerate interfacial mass transport and OER kinetics.
Benzhi Wang +8 more
wiley +1 more source
Cyclodextrins-Assisted Extraction for the Recovery of Bioactive Compounds from Rosemary Post-Distillation Residues-In Vitro Antioxidant Activity, Comparisons to Conventional Liquid Extracts. [PDF]
Tsitlakidou P +5 more
europepmc +1 more source
Essential oil fractions of hemp profiles at different hydro-distillation periods. [PDF]
Zheljazkov VD +7 more
europepmc +1 more source
The Dark Side of Green Energy: Glycol Waste and the Microbes That Can Transform It. [PDF]
Dybka JA +3 more
europepmc +1 more source

