Results 41 to 50 of about 351,367 (262)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Reliability Evaluation of Power System SVC Types Using a Markov Chain [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2015
Static reactive power compensator (SVC) plays an important role in power system reliability stems. In evaluations of reliability, only reactive power is considered as a constraint network is placed in the SVC Brrsy‌Ha impact on power system reliability ...
Ali Behdan, Bahador Fani, Ehsan Adib
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

PRICING OF REACTIVE POWER SERVICE [PDF]

open access: yesOil Shale, 2022
Rimantas Deksnys, R. Staniulis
doaj   +1 more source

Assessment of Daily Cost of Reactive Power Procurement by Smart Inverters

open access: yesEnergies, 2021
The reactive power control mechanisms at the smart inverters will affect the voltage profile, active power losses and the cost of reactive power procurement in a different way. Therefore, this paper presents an assessment of the cost–benefit relationship
Martha N. Acosta   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Submersible Compensator of Reactive Power

open access: yesElectricity
Enhancing the efficiency of mechanized oil production remains a critical objective in the industry. This paper presents a comparative analysis of existing methods aimed at improving the energy efficiency of oil extraction systems, outlining their ...
Vladimir Kopyrin   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An optimal reactive power pre-dispatch approach for minimizing active power losses

open access: yesFrontiers in Energy Research
Renewable energy sources (RES) depend on location and weather conditions, which can negatively impact the transmission system operator’s active power losses.
Daniel Baltensperger   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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