Results 71 to 80 of about 332,035 (262)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Reactive power limit of wind farm with doubly-fed induction generators and its asymmetric P-Q dependence

International Journal of Electrical Power & Energy Systems
The existing reactive power limit models of doubly-fed induction generators ignore the relation among wind speed, rotor speed, and active power output.
Shenghu Li
doaj   +1 more source

Reactive Power Contribution and Pricing for Restructured Power Industry [PDF]

Iraqi Journal for Electrical and Electronic Engineering, 2015
Competitive trend towards restructuring and unbundling of transmission services has resulted in the need renteto discover the impact of a particular generator to load.
Susithra.M, Gnanadass.R
doaj  

Reactive Power Compensation using Matrix Converter

Sukkur IBA Journal of Emerging Technologies, 2019
In this paper, application of matrix converter for the compensation of reactive power is studied. Matrix converter is direct AC-AC converter composed of solid-state bi-directional switches.
Muhammad Ishaq, Muhammad Hammad Afzal, Muhammad Waqar   +2 more
doaj   +1 more source

Analysis of Reactive Power Demand Based on Voltage-Reactive Power Correlation

Journal of Physics: Conference Series, 2019
AbstractThe inaccuracy of reactive power demand analysis in practical power system often leads to the problem of low voltage stability margin. In this paper, the analysis method of voltage-reactive power correlation is proposed, which is used to solve the inaccuracy of reactive power demand analysis. The proposed method can quickly analyze the reactive
Zhen Hu, Jian Zuo, Daojun Chen, Ting Cui, Ding Wang   +4 more
openaire   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Research on Reactive Power Coordination Control of Urban Rail Transit Power Monitoring System

Chengshi guidao jiaotong yanjiu
[Objective] The power supply system of urban rail transit mainly relies on the SVG (static var generator) or reactors in the 110 kV main substation for centralized reactive power compensation. The current control mode does not fully consider the reactive
ZOU Dayun, ZHAO Jiawei, XUE Zhong, WEI Zhixing, ZHANG Changkai, XIE Kai   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source