Results 61 to 70 of about 236,652 (295)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Reactive Power Optimization of Distribution Network Based on Random Matrix and Historical Scenario Matching

open access: yesZhongguo dianli, 2020
Reactive power optimization and voltage management of distribution networks is very important for the optimal operation of distribution networks. By introducing big data theory into reactive power optimization of distribution networks, a reactive power ...
Ran AN   +6 more
doaj   +1 more source

Reactive power optimization in large scale power systems

open access: yesInternational Journal of Electrical Power & Energy Systems, 1992
Abstract This paper presents a new optimization algorithm for solving reactive power compensation (RPC) problems in complex power systems. The algorithm optimizes the reactive power flow, and determines the total amount of capacitors required and allocates them in electrical networks.
M. Yehia   +3 more
openaire   +1 more source

Equilibrium Optimizer Algorithm for Optimal Reactive Power Dispatch

open access: yesJournal of Intelligent Systems: Theory and Applications, 2023
Optimal Reactive Power Dispatch (ORPD) is a significant research area in terms of maintaining the reliability and safety of the power system and operating it more economically. ORPD problem can be formed from a variety of perspectives including the minimization of the active power losses and voltage deviation, and improving the voltage stability ...
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

A Fast Reactive Power Optimization in Distribution Network Based on Large Random Matrix Theory and Data Analysis

open access: yesApplied Sciences, 2016
In this paper, a reactive power optimization method based on historical data is investigated to solve the dynamic reactive power optimization problem in distribution network.
Wanxing Sheng   +5 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Power system reactive power optimization based on MIPSO

open access: yesEnergy Procedia, 2012
AbstractIn order to improve power quality and reduce network losses, this paper proposes a modified immune particle swarm algorithm for power system reactive power optimization. To overcome the disadvantages in the traditional PSO algorithm about low accuracy and easy to fall into local optimal, MIPSO adopts sinusoidal changing inertia weight strategy ...
DingPing, Li   +5 more
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Dynamic reactive power planning method for CSP-PV hybrid power generation system

open access: yesJournal of Measurement Science and Instrumentation, 2020
Aiming at the faults of some weak nodes in the concentrated solar power-photovoltaic(CSP-PV) hybrid power generation system, it is impossible to restore the transient voltage only relying on the reactive power regulation capability of the system itself ...
ZHANG Hong   +4 more
doaj  

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