Results 61 to 70 of about 6,027,929 (265)
Journal of Experimental OrthopaedicsPurpose To investigate whether adding lateral extra‐articular tenodesis to anterior cruciate ligament reconstruction affects quadriceps strength or reactive strength at 6–8 months postoperatively in young, high‐risk athletes.
Mihail Lazar Mioc +3 more
doaj +1 more source
Neuromuscular control of the knee joint during basketball season in male youth players
Acta Gymnica, 2019 Background: Basketball players are among the players with a great risk of anterior cruciate ligament injury due to the high-intensity manoeuvres which have been identified as very common factors preceding this injury.
Matěj Strniště +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Establishing a Kinetic Assessment of Reactive Strength [PDF]
, 2017 Three neuromuscular characteristics are identified in Sheppard and Young’s model of agility: concentric strength and power, bilateral symmetry, and reactive strength.
Louder, Talin
core +1 more source
Assessing Plyometric Ability during Vertical Jumps Performed by Adults and Adolescents
Sports, 2018 The purpose of this study was to compare different methods for assessing plyometric ability during countermovement (CMJ) and drop jumps (DJ) in a group of adults and adolescents.
Brandon W. Snyder +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Concurrent Validity and Reliability of Three Ultra-Portable Vertical Jump Assessment Technologies
Sensors, 2020 Vertical jump is a valuable training, testing, and readiness monitoring tool used across a multitude of sport settings. However, accurate field analysis has not always been readily available or affordable.
Casey M. Watkins +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source