Results 111 to 120 of about 16,917,031 (330)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Theory of weakly nonlinear self sustained detonations

, 2014
We propose a theory of weakly nonlinear multi-dimensional self sustained detonations based on asymptotic analysis of the reactive compressible Navier-Stokes equations.
Faria, Luiz M., Kasimov, Aslan R., Rosales, Rodolfo R.   +2 more
core  

Modelling magnetism of C at O and B monovacancies in graphene

, 2013
The presence of defects can introduce important changes in the electronic structure of graphene, leading to phenomena such as C magnetism. In addition, vacancies are reactive and permit the incorporation of dopants.
Faccio, R., Kahaly, M. Upadhyay, Kaloni, T. P., Schwingenschlögl, U.   +3 more
core   +1 more source

Synthesis, characterization and application of novel bisazo reactive dyes on various fibers

Orbital: The Electronic Journal of Chemistry, 2011
Ten hot brand bisazo reactive dyes (D1 to D10) have been synthesized by coupling bis(diazotised), 4,4'-methylene bis(2,6-dichloroaniline) (A) with various 5-sulfo anthranilo cyanurated coupling components (R) and their dyeing performance as ...
Divyesh R. Patel, Nikul S. Patel, Hemant S. Patel, Keshav C. Patel   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Fair Clearing of Reactive Power Market

Majlesi Journal of Electrical Engineering
In this paper, new reactive power market structure is studied and presented. Active power flow by itself causes active and reactive losses. Considering reactive losses of active power flow in the reactive power market without paying any costs is the main
Alireza Ahmadimanesh, Mohsen Kalantar
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Voice reactive biomimetic structure

IOP Conference Series: Materials Science and Engineering, 2018
The paper presents a Biomimetic Structures Reactive to Voice Commands (BSRVC). By sending voice commands the BSRVC will achieve the different emotional states. These states are controlled by a negative feedback control system with changed reference for each emotional state.
M Ionescu, I Borcoşi, N G Bîzdoacă
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source