Results 71 to 80 of about 8,573 (198)

Markedly increased small-sized megakaryocytes and platelets count in the circulation with pseudo-hyperkalemia following splenectomy

European Journal of Medical Research, 2022
Megakaryocytes are common in the bone marrow and appear less often in circulation. Most studies on circulatory megakaryocytes have implicated myelodysplastic syndromes and myeloproliferative disorders because of disruption of the bone marrow barrier and ...
Guiying Li, Bin Wang, Dongyan Li, Rong Zhu, Xueyan Chen   +4 more
doaj   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

British Journal of Haematology, EarlyView.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed, Rattanaporn Praneetponkang, Potchaman Sittipaisankul, Chayada Thiengtavor, Suwathida Chumpuchanaphai, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Duncan R. Smith, Saovaros Svasti, Pornthip Chaichompoo   +11 more
wiley   +1 more source

Incidence of Reactive Thrombocytosis in Febrile Young Infants with Serious Bacterial Infections

, 2016
The purpose of the present prospective study, conducted in a tertiary care paediatric unit during June 2013 to October 2014, was to estimate the incidence of reactive thrombocytosis among febrile young infants and assess the utility of platelet count as ...
Bobby Sadawarti, Anuj Sethi, O S Chaurasiya, R S Sethi   +3 more
core   +1 more source

A Multimodal Strategy for Perioperative Reactive Thrombocytosis in Gynaecologic Cancer Surgery - A Case Report

Journal of Onco-Anaesthesiology and Perioperative Medicine
Reactive thrombocytosis, defined as platelet count >450 × 103/µL, can pose perioperative thrombotic and bleeding risk. We present the case of a 47-year-old woman with bilateral ovarian masses, uterine fibroids and pelvic abscess, whose platelet count ...
Gitartha Goswami, Prashant Sirohiya, Balbir Kumar, Brajesh Kumar Ratre   +3 more
doaj   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Extreme thrombocytosis in traumatic amputee and role of thromboembolism prophylaxis: a case report

, 2023
Platelets are the smallest blood component produced in the bone marrow that plays a fundamental role in the blood clotting process. A normal platelet count applicable to all adults is 150 to 400×109/l.
Sharma, Pulak, Sharma, Swati, Gunjiganvi, Mallikarjun, Bhalchandra, Awale R.   +3 more
core   +2 more sources

Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia

European Journal of Haematology, EarlyView.
ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco, Diane S. Krause, Sara T. Olalla Saad   +2 more
wiley   +1 more source

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, EarlyView.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source

Does Thrombocyte Size Give Us an Idea about Thrombocytosis Etiology?

The Scientific World Journal, 2012
In the presence of a pathogenetic mutation in JAK2 or MPL, a differential diagnosis of essential thrombocythemia (ET) from reactive causes is relatively simple.
Selami Kocak Toprak, Betul Erismis, Sema Karakus, Nazmiye Kursun, Aysegul Haberal, Mustafa Gurhan Ulusoy   +5 more
doaj   +1 more source

Childhood primary myelofibrosis presented with headache, splenomegaly, and severe thrombocytosis: A case report

Indian Journal of Medical and Paediatric Oncology, 2018
Primary myelofibrosis (PMF) is a clonal disorder of a multipotent hematopoietic progenitor cell that occurs predominantly in the elderly age group. We report here an 11-year-old girl who presented with headache, fever, and splenomegaly.
Athanasios Tragiannidis, Athanasia Apsemidou, Ioannis Liampas, Triantafyllia Koletsa   +3 more
doaj   +1 more source