Results 131 to 140 of about 844,980 (316)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Monte Carlo Modelling of Void Coefficient of Reactivity Experiment [PDF]
, 2010 The Atominstitute (ATI) of the Vienna University of Technology utilizes a TRIGA Mark II research reactor for last fourty eight years at a nominal reactor power of 250 kW (thermal).
Khan, R., Böck, Helmuth, Villa, Mario
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Reactivity Hypothesis adult reactivity versus child reactivity
The phenomenom of reactivity is such that if one tells a person that the person is recorded each time the person says the word 'like' the person is saying it less than if the person would have not known the word is going to be recorded, i.e. the person being monitored. A good example is described in the book David H. Barlow & V. Mark Durand, 2012, 2009
openaire +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Synergistic Effects in Co-Gasification of Willow and Cedar Blended Char in CO2 Media
EnergiesWillow is a promising biomass resource for addressing the challenges of securing stable domestic biomass fuels in Japan and utilising abandoned agricultural land.
Kenji Koido +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Towards Construction of the “Periodic Table” of 1-Methylbenzotriazole
InorganicsMetal complexes of benzotriazole-type ligands continue to attract the intense interest of many inorganic chemistry groups around the world for a variety of reasons, including their aesthetically beautiful structures, physical properties and applications.
Christina Stamou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
StressLaboratory stress tasks are necessary to closely investigate the stress response in a controlled environment. However, to our knowledge, no study has tested whether participating in such tasks can pose any daily life adverse effect.
Joana De Calheiros Velozo +3 more
doaj +1 more source