Results 141 to 150 of about 1,806,003 (362)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Towards Construction of the “Periodic Table” of 1-Methylbenzotriazole
Metal complexes of benzotriazole-type ligands continue to attract the intense interest of many inorganic chemistry groups around the world for a variety of reasons, including their aesthetically beautiful structures, physical properties and applications.
Christina Stamou +4 more
doaj +1 more source
Reactivity of Cyclopropenylaluminates
Reactions of the potassium cyclopropenylaluminates, [{SiNDipp}-Al-η2-(C2Ph2)-K] and [{SiNDipp}-Al-η2-(PhCCSiMe3)-K] with terminal alkynes provide alkynylvinylaluminate derivatives with the silyl-substituted analog providing a level of kinetic discrimination. While this latter behavior results in the regiochemical protonation at Al-C-(Ph) and retention
Marco F. Starostzik +4 more
openaire +3 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Laboratory stress tasks are necessary to closely investigate the stress response in a controlled environment. However, to our knowledge, no study has tested whether participating in such tasks can pose any daily life adverse effect.
Joana De Calheiros Velozo +3 more
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Reactivity without legitimacy? Online consumer reviews in the restaurant industry
Jean-Samuel Beuscart +2 more
openalex +2 more sources
PKD1 protein is involved in reactive oxygen species-mediated mitochondrial depolarization in cooperation with protein kinase Cδ (PKCδ). [PDF]
Tianzhou Zhang +3 more
openalex +1 more source

