Results 181 to 190 of about 1,806,003 (362)

Reactive Hyperinsulinism [PDF]

BMJ, 1944
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A robotic approach to polymerisation kinetics: a case study on copolymerisation parameter estimation. [PDF]

Chem Sci
Alexander L, Jafari VF, Junkers T.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

CYP2C19 Polymorphism and Platelet Aggregation-Associated Risks in Atrial Fibrillation Patients Undergoing PCI. [PDF]

Clin Transl Sci
Gjermeni D, Szabó S, Anfang V, Vetter H, Juelch C, Rademacher S, Li T, Leggewie S, Hesselbarth D, Duerschmied D, Trenk D, Westermann D, Olivier CB.   +12 more
europepmc   +1 more source

Photoinitiator-free Photo-reactive Coloration of Wool Fabrics Using C.I. Reactive Black 5 [PDF]

, 2012
Yuanyuan Dong, Jin-Ho Jang
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Evolution of Char Structure and Its Influence on Reactivity During Biomass Pyrolysis: Spatial Scale Effects from Pellet Size to Intra-Pellet Location. [PDF]

Polymers (Basel)
Liu H, Yu Y, Wu J, Huang J, Hu W, Xia L, Ru Y, Zhang M, Xu M, Qiao Y.   +9 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The role of dopamine decline, astrocyte reactivity, and cerebral small-vessel disease in cognitive aging. [PDF]

J Cereb Blood Flow Metab
Crine V, Johansson J, Ericsson O, Wåhlin A, Axelsson J, Anderssson M, Nyberg L, Karalija N.   +7 more
europepmc   +1 more source