Results 221 to 230 of about 1,806,003 (362)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Cysteinylated Protein as Reactive Disulfide: An Alternative Route to Affinity Labeling

open access: green, 2007
Zheng Miao   +6 more
openalex   +2 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Multi-country IgE reactivity determination of isoforms of the <i>Blomia tropicalis</i> mite allergen Blo t 2 revealed a potential biomarker of asthma severity. [PDF]

open access: yesFront Immunol
Urrego JR   +13 more
europepmc   +1 more source

Reactivate

open access: yesCanadian Journal of Rural Medicine
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Therapeutic effects of a synthetic peptide of C-reactive protein in pre-clinical tumor models

open access: green, 1993
Barbara P. Barna   +6 more
openalex   +2 more sources

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