Results 141 to 150 of about 1,442,979 (244)
Biotechnology and Bioengineering, EarlyView.ABSTRACT Accurate prediction of bioprocess scale‐up is critical for accelerating the deployment of novel and sustainable biomanufacturing systems. However, this remains challenging as multi‐scale data is expensive to generate and mechanistic understanding is often incomplete, leading upscaling decisions to rely heavily on empirical expertise. This work
Harvey Al‐Ramadhan +3 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng +3 more
wiley +1 more source
Preparation of guidance for health risk assessment of environmental noise
, 2010 Evidence has accumulated regarding health effects of environmental noise. The WHO European Centre for Environment and Health, Bonn, has organized several meetings of experts over recent years to examine the current state of knowledge, and to further ...
Brown, AL +4 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly +7 more
wiley +1 more source
Batch‐to‐Batch Optimization of pH Shifts in CHO Bioreactor Operations
Biotechnology and Bioengineering, EarlyView.ABSTRACT Culture pH is an important operating parameter in CHO cell cultures producing mAb since it directly affects growth and specific productivity. Mathematical models can be used to optimize the magnitude and timing of pH shifts provided that they are robust to model errors.
Ali Ghodba +6 more
wiley +1 more source
BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng +4 more
wiley +1 more source
Biotechnology Progress, EarlyView.SIM‐CaliRam combines simulation‐informed references and biomass‐augmented features for in‐line Raman calibration under sparse labels and biomass‐induced spectral confounding. Run‐wise calibration and validation enable prediction of biomass, glucose, ammonium, and phosphate on an unseen S. cerevisiae fed‐batch fermentation.
Terrance Wilms, Steffi Knorn
wiley +1 more source
Carbon Energy, EarlyView.This review reveals how electronic configuration engineering governs the entire electrocatalytic nitrogen cycle, providing structure‐informed insights into reaction selectivity, catalytic durability, and sustainable nitrogen utilization across energy and environmental systems. ABSTRACT The global nitrogen cycle is essential to food production, chemical
Jiamu Feng +7 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.New insights into the mechanism of the structural transformation of cellulose into highly ordered graphitic carbon using an Fe–Ca bimetallic catalyst were obtained through complementary spectroscopic techniques, including Raman, solid‐state NMR, and Mössbauer.
Shamala Gowri Krishnan +3 more
wiley +1 more source
Carbon Innovation, EarlyView.Synthesis and characterization of sugarcane bagasse‐derived activated carbon via KOH‐assisted dry and wet activation. ABSTRACT This study explores the impact of activation processes on the morphological properties of activated carbon. Carbon is initially produced through vacuum pyrolysis at three temperatures (500°C, 600°C, and 700°C), with a heating ...
Sachin Channappa Hallad +5 more
wiley +1 more source