Results 71 to 80 of about 3,020,549 (269)

Enhanced Production of Cellulase from the Agricultural By-product Rice bran by Escherichia coli JM109/LBH-10 with a Shift in Vessel Pressure of a Pilot-scale Bioreactor

BioResources, 2016
The optimal vessel pressure of the bioreactor for cell growth and the production of cellulase, as well as the effect of a shift in pressure within the reactor on cellulase production were investigated. The optimal vessel pressure for the cell growth of E.
Chi-Jong Jong, Yong-Suk Lee, Jin-Woo Lee
doaj   +1 more source

Pressure vessel design manual

, 2013
Pressure vessels are closed containers designed to hold gases or liquids at a pressure substantially different from the ambient pressure. They have a variety of applications in industry, including in oil refineries, nuclear reactors, vehicle airbrake ...
Moss, Dennis R, Basic, Michael, Basic, Michael., Moss, Dennis R.   +3 more
core  

High Cell Density Cultivation of HEK293 Cells Using a 2L Membrane‐Stirred Bioreactor

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The use of perfusion systems for the continuous cultivation of animal cells at high cell density (HCD) for the production of recombinant proteins, viruses, and viral vectors has many advantages. Besides an enhancement of volumetric productivity and high cell viability, the product quality can be improved through a steady‐state environment ...
Lennart Jacobtorweihe, Yasemin van Heuvel, Kathrina Scheiermann, Patrick Bongartz, Yvonne Genzel, Udo Reichl   +5 more
wiley   +1 more source

Model‐Driven Monitoring and Parameter‐Based Development of an Escherichia coli Fed‐Batch Process for Production of a Fab Antibody Fragment Across Scales

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg, Lucas Kaspersetz, Markus Zoellkau, Markus Glaser, Markus Brunner, Christian Bosch, Annina Kemmer, M. Nicolas Cruz Bournazou, Peter Neubauer   +8 more
wiley   +1 more source

Design basis accident analysis of a small modular reactor

Journal of Thermal Engineering, 2017
The International Reactor Innovative and Secure (IRIS) is an integrated small modular reactor (SMR) designed by Westinghouse Electric Company and a consortium of organizations.
Jivan Khatry, Fatih Aydogan
doaj  

Validation of the code package MCPV [PDF]

Ядерна фізика та енергетика, 2009
The results of the validation of the code package MCPV that is used in the radiation exposure determination methodology for the pressure vessels of the VVER type reactors of Ukrainian NPPs are presented.
V. N. Bukanov, O. V. Grytsenko, V. L. Diemokhin, O. M. Pugach, S. M. Pugach   +4 more
doaj  

Investigation on Integrity of JMTR Reactor Pressure Vessel

, 2010
Visual observation of inner side of a reactor pressure vessel of Japan Materials Testing Reactor (JMTR) was carried out using an underwater camera before the JMTR refurbishment work from the view point of its long term utilization, because the reactor ...
Yoshiharu Nagao, Hiroshi Miura, Hiroshi Ide, Akihiro Kimura, Masanori Kaminaga, Naohiko Hori   +5 more
core   +1 more source

A General Workflow for Tangential Flow Filtration Perfusion Scale‐Up

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) perfusion using hollow‐fiber modules offers substantial advantages over other mammalian cell retention technologies. Recently, increased awareness of Starling flow has helped to enhance filtration performance to similar, or even higher levels compared to alternative technologies.
Patrick Romann, Ken Lee, Venkatesh Natarajan, Daniel Ley, Claes Nymand Nilsson, David Garcia‐Munzer, Dominik Schieman, Mahbod Hajighasemi, Alex Zaytsev, Jason Friedman, Loic Chappuis, Tobias Habicher, Colin Jaques, Alex Cohen, Matthew Gagnon, Edward Chan, Daniel J. Karst, Philip Giller, Antony Sibilia, Andrew L. Zydney, Thomas K. Villiger   +20 more
wiley   +1 more source

The Integral Test Facility Karlstein

Science and Technology of Nuclear Installations, 2012
The Integral Test Facility Karlstein (INKA) test facility was designed and erected to test the performance of the passive safety systems of KERENA, the new AREVA Boiling Water Reactor design.
Stephan Leyer, Michael Wich
doaj   +1 more source

Reducing Cooling Costs for Sustainable Food Biomanufacturing With Thermotolerant Cupriavidus necator H16 Mutant

Biotechnology and Bioengineering, EarlyView.
With a thermotolerant C. necator mutant the SCP production costs can be decreased by $0.98/kg. ABSTRACT Autotrophic CO2 conversion to Single Cell Protein (SCP) using H2 and O2 is gaining commercial traction for food and feed production. Cupriavidus necator H16 is a key chassis organism for this “knallgas” fermentation, but industrial operation is ...
Lars Puiman, James Kemp Heffernan, Esteban Marcellin   +2 more
wiley   +1 more source