Results 121 to 130 of about 1,362,093 (292)
, 1984 Survival: the key is your desire to live -- O'Dowd speaks out: University needs to become more unified -- Eaglecrest on an uphill glide -- Diet critical for maintaining health -- Watergate: Then and now -- Editorial page -- Bruce Cockburn: The new age ...
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Novel approach for efficient predictions properties of large pool of nanomaterials based on limited set of species: nano-read-across [PDF]
Creating suitable chemical categories and developing read-across methods, supported by quantum mechanical calculations, can be an effective solution to solving key problems related to current scarcity of data on the toxicity of various nanoparticles ...
Cronin, MTD +4 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Testing Strategies for the Prediction of Skin and Eye Irritation and Corrosion for Regulatory Purposes [PDF]
, 2007 This report reviews the use of stepwise testing approaches for the prediction of skin and eye irritation and corrosion in a regulatory context. It is published as a companion report to the "Review of Literature-Based Models for Skin and Eye Irritation ...
GALLEGOS SALINER Ana, WORTH Andrew
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Next SustainabilityThis study employs a read-across approach, generating similarity-based hypotheses to predict the removal efficiency of VOCs (Volatile Organic Compounds) during the recycling of plastic film waste. The objective was to estimate VOC emissions under various
Md Mobarak Hossain, Kunal Roy
doaj +1 more source
The use of the t-teste in language studies [PDF]
, 1990 Chapter ThreeZadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 zostało dofinansowane ze środków MNiSW w ramach działalności ...
Weinstein, Marc
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Application of read-across methods as a framework for the estimation of emissions from chemical processes. [PDF]
Clean Technol Recycl, 2023 Takkellapati S, Gonzalez MA.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source