5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
NO-TILL PROVIDES THE OPPORTUNITY TO MANAGE UNDERGROUND INTERACTIONS BETWEEN ARBUSCULAR MYCORRHIZAL FUNGI, WEEDS AND CROP PLANTS UNDER MEDITERRANEAN CONDITIONS [PDF]
Early colonization of crop roots by arbuscular mycorrhiza (AM) is considered beneficial but its importance likely depends on the possible stresses faced by the host plant. Manganese toxicity is one such stress that AM can alleviate.
Alho, Luís +3 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Veiling and unveiling: Mansfield's modernist aesthetics [PDF]
The wearing of a veil like other fashionable items of attire in Mansfield’s fiction ‒ parasols, hats, gloves, muffs, and hair ribbons ‒ usually serves more than mere decoration, protection or fashion.
Wilson, Janet M
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki +8 more
wiley +1 more source
Thermal Effects on Monolithic 3D Ferroelectric Transistors for Deep Neural Networks Performance
Monolithic three‐dimensional (M3D) integration advances integrated circuits by enhancing density and energy efficiency. Ferroelectric thin‐film transistors (Fe‐TFTs) attract attention for neuromorphic computing and back‐end‐of‐the‐line (BEOL ...
Shubham Kumar +2 more
doaj +1 more source
SOLAR ERUPTION ON 4 JANUARY 2011: CASE STUDY FOR SPACE EARLY WARNING [PDF]
We perform intuitive analysis for solar eruption on 4 January 2011. Since we do not have magnetic observational data from the eruption, we perform first order calculation and expands it as interplanetary total effect of energy propagation by retro ...
Bambang, Setiahadi
core

