Results 51 to 60 of about 1,069,051 (295)

Observing sub-microsecond telegraph noise with the radio frequency single electron transistor

, 2004
Telegraph noise, which originates from the switching of charge between meta-stable trapping sites, becomes increasingly important as device sizes approach the nano-scale.
Buehler, T. M., Chan, V. C., Clark, R. G., Dzurak, A. S., Hamilton, A. R., Reilly, D. J., Starrett, R. P.   +6 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Low Noise Signal Read-Out Circuit for Integrated Quantum Diamond Magnetometers

IEEE Transactions on Quantum Engineering
A customized low-noise signal read-out circuit, which is designed for the implementation of the integrated low power consumption quantum magnetometers based on nitrogen-vacancy centers in diamond, is reported in this article. As the circuit has a 3.7 pA&#
Zhenlin Zhang, Wenzhe Zhang, Enrui Zhang, Xi Qin   +3 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Working With Environmental Noise and Noise-Cancelation: A Workload Assessment With EEG and Subjective Measures

Frontiers in Neuroscience, 2021
As working and learning environments become open and flexible, people are also potentially surrounded by ambient noise, which causes an increase in mental workload.
Kerstin Pieper, Robert P. Spang, Pablo Prietz, Sebastian Möller, Sebastian Möller, Erkki Paajanen, Markus Vaalgamaa, Jan-Niklas Voigt-Antons, Jan-Niklas Voigt-Antons   +8 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Performance Degradation in Static Random Access Memory of 10 nm Node FinFET Owing to Displacement Defects

Micromachines, 2023
We comprehensively investigate displacement-defect-induced current and static noise margin variations in six-transistor (6T) static random access memory (SRAM) based on a 10 nm node fin field-effect transistor (FinFET) using technology computer-aided ...
Minji Bang, Jonghyeon Ha, Gyeongyeop Lee, Minki Suh, Jungsik Kim   +4 more
doaj   +1 more source

Sensitivity of the spherical gravitational wave detector MiniGRAIL operating at 5 K [PDF]

, 2007
We present the performances and the strain sensitivity of the first spherical gravitational wave detector equipped with a capacitive transducer and read out by a low noise two-stage SQUID amplifier and operated at a temperature of 5 K.
Bassan, M., de Waard, A., Fafone, V., Flokstra, J., Frossati, G., Gottardi, L., Minenkov, Y., Podt, M., Rocchi, A., Usenko, A.   +9 more
core   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Illuminating the dark side of the human transcriptome with long read transcript sequencing

BMC Genomics, 2020
Background The human transcriptome annotation is regarded as one of the most complete of any eukaryotic species. However, limitations in sequencing technologies have biased the annotation toward multi-exonic protein coding genes. Accurate high-throughput
Richard I. Kuo, Yuanyuan Cheng, Runxuan Zhang, John W. S. Brown, Jacqueline Smith, Alan L. Archibald, David W. Burt   +6 more
doaj   +1 more source