Results 51 to 60 of about 255,822 (257)

Optimizing the Limit of Detection of Waveguide-Based Interferometric Biosensor Devices

Sensors, 2019
Waveguide-based photonic sensors provide a unique combination of high sensitivity, compact size and label-free, multiplexed operation. Interferometric configurations furthermore enable a simple, fixed-wavelength read-out making them particularly suitable
Jonas Leuermann, Adrián Fernández-Gavela, Antonia Torres-Cubillo, Sergio Postigo, Alejandro Sánchez-Postigo, Laura M. Lechuga, Robert Halir, Íñigo Molina-Fernández   +7 more
doaj   +1 more source

Direct-reading dial for noise temperature and noise resistance

Electronics Letters, 1967
An attenuator arrangement for a noise generator is described. The scheme permits direct reading of both noise resistance and noise temperature—the latter with a choice of source resistance.
openaire   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Ultra-Low Power High Stability 8T SRAM for Application in Object Tracking System

IEEE Access, 2018
In this paper, an ultra-low power (ULP) 8T static random access memory (SRAM) is proposed. The proposed SRAM shows better results as compared with conventional SRAMs in terms of leakage power, write static noise margin, write-ability, read margin, and ...
Pooran Singh, Santosh Kumar Vishvakarma
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

HKROC: An integrated front-end ASIC to read out photomultiplier tubes for large neutrino experiments [PDF]

EPJ Web of Conferences
The HKROC ASIC was originally designed to read out the photomultiplier tubes (PMTs) for the Hyper-Kamiokande (HK) experiment. HKROC is a very innovative ASIC capable to read out a large number of channels satisfying stringent requirements in terms of ...
Dulucq Frederic, Beauchêne Antoine, Bolognesi Sara, Bouyjou Florent, Carabadjac Denis, Conforti Di Lorenzo Selma, Firlej Miroslaw, Fiutowski Tomasz, Gastaldi Franck, Guilloux Fabrice, Idzik Marek, de La Taille Christophe, Moron Jakub, Nanni Jerome, Quilain Benjamin, Rogly Rudolph, Swientek Krzysztof, Thienpont Damien   +17 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Ultra-low Power FinFET SRAM Cell with Improved Stability Suitable for Low Power Applications [PDF]

International Journal of Electronics and Telecommunications, 2019
In this paper, a new 11T SRAM cell using FinFET technology has been proposed, the basic component of the cell is the 6T SRAM cell with 4 NMOS access transistors to improve the stability and also makes it a dual port memory cell.
Shilpi Birla
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source